Results 201 to 210 of about 3,091,998 (362)
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
Will 'Support at Home' Deliver What Older People Want? [PDF]
Laragy C, McVilly K.
europepmc +1 more source
Perceptual independence of pulse rates used in speech coding schemes for a multichannel cochlear implant [PDF]
Wai Kong Lai +4 more
openalex +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Securing independence in global health oversight-the OPEN framework. [PDF]
Schwalbe N +3 more
europepmc +1 more source
LEARNING GUIDANCE AS AN EFFORT TO CREATE STUDENT LEARNING INDEPENDENCE
Annisa Puji Rahayu +3 more
openalex +1 more source
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Is Continuous Disclosure Associated with Board Independence
Zoltan Matolcsy, Peter Wells
openalex +1 more source

