Results 221 to 230 of about 948,462 (255)

Predictors of Paid Employment Status Among Individuals With Spinal Cord Injury in South Korea: An Exploratory Study Using Random Forest Analysis. [PDF]

Ann Rehabil Med
Song K, Lim J, Kim O.
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

An umbrella review of systematic reviews and meta-analyses evaluating the efficacy and safety of mechanical thrombectomy for acute ischemic stroke. [PDF]

Ann Med Surg (Lond)
Aderinto N, Oyediran TO, Abioye AH, Ezeakunne HC, Oyedele TJ.   +4 more
europepmc   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Correction to "Balanced Parenting: Proposing a Differentiation-Based Parenting Approach Informed by Bowen Family Systems Theory". [PDF]

Fam Process
europepmc   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Clinical Outcomes Following Bilateral Implantation of TECNIS Odyssey Intraocular Lenses in Japanese Eyes. [PDF]

Clin Ophthalmol
Yuen C, Keahi CL, Dutton S, Yuen CK, Dunn AK, Hall B.   +5 more
europepmc   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Metagenome-scale modeling to assess microbiome metabolic complementarity for precision microbiota transplantation therapies. [PDF]

Gut Microbes
Zhang Z, Holton M, Ferrer DM, Tripp AD, Richter A, Dixit PD, Urtecho G.   +6 more
europepmc   +1 more source

Energy Cost of Walking in Relation to Impairment and Functional Independence After Stroke: The Role of Walking Speed. [PDF]

Physiother Res Int
Guediri A, Compagnat M, Poyet A, Daviet JC, Mandigout S.   +4 more
europepmc   +1 more source