Results 251 to 260 of about 2,862,918 (376)

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Limited open repair for achilles tendon rupture in the setting of co-morbidities: A case series and technique review

Foot & Ankle Surgery: Techniques, Reports & Cases
An acute Achilles tendon rupture poses a difficult treatment strategy in both young and old patients. Commonly considered an injury of the middle aged “weekend warrior,” an Achilles tendon tear in a sedentary patient is quite debilitating.
James C. Connors, DPM, FACFAS, Mark A. Hardy, DPM, FACFAS, Halle L. Krebs, Ali A. Manji, DPM, Cory M. Jarosi, DPM   +4 more
doaj  

Quantitative contrast enhancement volume on immediate post-thrombectomy CT predicts symptomatic intracranial hemorrhage and functional outcomes in acute large vessel occlusion stroke. [PDF]

Front Neurol
Huang Z, Xiong Z, Gong C, Jiang S, Huang L, Wang Y, Yuan J, Gao Y, Ban Y, Chen Y, Xu T.   +10 more
europepmc   +1 more source

INDEPENDENCE OF THE GOITER DEVELOPMENT TO THE CONCENTRATION OF CIRCULATING PROTEIN BOUND IODINE

, 1957
K Shichijo, Takashi Yamada, Toshikazu Shimizu   +2 more
openalex   +2 more sources

Landscape of BRAF transcript variants in human cancer

Molecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda, Danilo Tatoni, Gianluca Mattei, Alberto Magi, Romina D'Aurizio, Laura Poliseno   +5 more
wiley   +1 more source

Utility of the Short Physical Performance Battery for Determining Walking Independence in Patients With Stroke. [PDF]

Cureus
Kajiwara S, Maruyama M, Oikawa T, Horikawa M, Sasaki M.   +4 more
europepmc   +1 more source

1925 catalogue of the Independence Nurseries, landscape gardeners and general nurserymen, water lilies and fancy fish /

, 1925
A. S. Buskirk
openalex   +2 more sources

Independence of Faris-rejection-axioms. [PDF]

, 1960
Ivo Thomas
openalex   +1 more source

Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren, Moana Busch, Pedro A. Ruiz, Ermanno Malagola, Valeria Baumeler, Federica Foti, Adelina Gross, Tobias Grütter, Hendrik Edel, Cordelia Schuler, Kristina Handler, Glenn De Lange, Isabelle C. Arnold, Cheryl de Vallière, Klaus Seuwen, Martin Hausmann, Gerhard Rogler   +16 more
wiley   +1 more source

Femtosecond laser-assisted lens exchange with trifocal intraocular lens in a patient with albinism and nystagmus. [PDF]

Int J Surg Case Rep
Zhu Y, Chen L, Zhao T, Zhang S.
europepmc   +1 more source