Results 261 to 270 of about 761,422 (315)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Quality of Life and Related Factors in Children With Dystonia. [PDF]

Brain Behav
Uzun Akkaya K, Serdaroglu E, Atalan Efkere P, Basaran Z, Elbasan B.   +4 more
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Independence in activities of daily living for home-based geriatric rehabilitation after shortened inpatient rehabilitation: The “Better@Home” multicentre prospective cohort study with a matched historical control group.

Gamble C, Vaz M, de Waal M, Groen W, Pol M, Isselt EvDv, Innocenti F, Zwakhalen S, Haastregt Jv.   +8 more
europepmc   +1 more source

Association between periodontal and geriatric health: a cross-sectional study. [PDF]

Clin Oral Investig
Müller ML, Deschner J, Mohr M, Mildenberger PC, Hardt R, Kiramira D.   +5 more
europepmc   +1 more source

Independent Walking at Discharge in Nonsurgical Patients With Thalamic Hemorrhage Who Were Nonambulatory on Day 14: A Retrospective Study of Prognostic Factors. [PDF]

Cureus
Fujita A, Hagii J, Tsuda E.
europepmc   +1 more source

Cost Effectiveness of Endovascular Thrombectomy for Large Ischemic Strokes: A US Healthcare Payer Markov Model Informed by Randomized Trials. [PDF]

Appl Health Econ Health Policy
Morsi RZ, Zhang Y, Badillo Goicoechea E, Desai H, Kothari SA, Thind S, Baskaran AB, Chahine A, Siegler JE, Coleman ER, Brorson JR, Mansour A, Prabhakaran S, Kass-Hout T.   +13 more
europepmc   +1 more source

Commentary: Field-based measurement tools to distinguish clonal <i>Typha</i> taxa and estimate biomass: a resource for conservation and restoration. [PDF]

Front Plant Sci
Elgersma KJ, Aird S, Martina JP, Goldberg DE.   +3 more
europepmc   +1 more source