Results 81 to 90 of about 872,295 (296)

Complete mitogenome of the ixodid tick Dermacentor reticulatus (Acari: Ixodida)

Mitochondrial DNA. Part B. Resources, 2020
Here, we present the complete mitochondrial DNA sequence of Dermacentor reticulatus. The mitogenome is 14,806 bp and contains 13 protein-coding, 2 rRNA, and 22 tRNA genes, along with 2 control regions.
Mikhail Yu Kartashov, Alexander N. Shvalov, Natalya L. Tupota, Vladimir N. Romanenko, Nina S. Moskvitina, Vladimir A. Ternovoi, Valery B. Loktev   +6 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

BRITISH AND NIGERIA’S UNDERDEVELOPMENT: REVISIT ANALYSIS

International Studies Journal
This paper examines the concept of imperialism which has been implicated in the underdevelopment of Nigeria like other African Countries where it had been at work While they had long operated in Nigeria, new Imperialism that relates to colonialism is ...
INDEPENDENCE C. ENYINDAH, FRANK O. AMUGO   +1 more
doaj  

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Assessing the influence of fiscal and monetary policies on carbon dioxide emissions

Latin American Journal of Central Banking
This paper examines the impact of fiscal and monetary policies on carbon dioxide emissions in Trinidad and Tobago, using data from 1970 to 2020. We use a fiscal policy index based on government revenue and expenditure, a monetary policy index based on ...
Avinash Ramlogan, Andell Nelson
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Association of Urinary Equol Concentration with Frailty in Community-Dwelling Older Adults: The Itabashi Longitudinal Study on Aging

Clinical Interventions in Aging
Narumi Kojima,1 Takashi Shida,1 Takahisa Ohta,1 Keiko Motokawa,2 Tsuyoshi Okamura,3 Hirohiko Hirano,2 Hiroyuki Sasai1 1Frailty and Musculoskeletal Health Research, Research Team for Promoting Independence and Mental Health, Tokyo Metropolitan Institute ...
Kojima N, Shida T, Ohta T, Motokawa K, Okamura T, Hirano H, Sasai H   +6 more
doaj  

A Generic Sure Independence Screening Procedure

Journal of the American Statistical Association, 2018
Extracting important features from ultra-high dimensional data is one of the primary tasks in statistical learning, information theory, precision medicine, and biological discovery.
Wenliang Pan, Xueqin Wang, Weinan Xiao, Hongtu Zhu   +3 more
semanticscholar   +1 more source