Results 81 to 90 of about 651,740 (292)
Landscape of BRAF transcript variants in human cancer
Molecular Oncology, EarlyView.We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop +10 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau +9 more
wiley +1 more source
Quantitative Safety Analysis of Train Control System Considering Common Cause Failure
Kongzhi Yu Xinxi JishuThe train control system, a safety-related component pivotal for ensuring the operational safety of trains, is prone to causing common cause failures (CCF) due to its multi-channel redundancy design.
LUO Jiguang
doaj +1 more source
FEBS Open Bio, EarlyView.Ca2+‐mediated response to DMSO was investigated in Saccharomyces cerevisiae cells expressing Ca2+‐dependent aequorin. Cell exposure to DMSO induced a cytosolic Ca2+ wave dependent on the integrity of the Cch1/Mid1 channel. Deletion of KCS1 or VIP1 genes encoding the phosphoinositol pyrophosphate (PP‐IP) synthases suppressed the DMSO‐induced Ca2 ...
Larisa Ioana Gogianu +4 more
wiley +1 more source
Cumulants, Spreadability and the Campbell-Baker-Hausdorff Series
, 2019 We define spreadability systems as a generalization of exchangeability systems in order to unify various notions of independence and cumulants known in noncommutative probability.
Hasebe, Takahiro, Lehner, Franz
core +1 more source
Journal of Applied Clinical Medical Physics, EarlyView.Abstract The establishment of guidelines and curriculum standards for medical physics residency training is a critical component of setting expectations and competencies for the profession. Since the last publication of these standards, residency training has become integrated into the eligibility criteria for most medical physics certification bodies.
Jonathon A. Nye +16 more
wiley +1 more source
La objetividad del azar en un mundo determinista
Crítica, 2018 This paper deals with the notion of objective randomness in classical deterministic theories. After the introduction, section 2 establishes an important distinction between a strictly metaphysical thesis of determinism (as characterized in the Montague ...
Sergio Martínez
doaj +1 more source
Causal inference using the algorithmic Markov condition
, 2008 Inferring the causal structure that links n observables is usually based upon detecting statistical dependences and choosing simple graphs that make the joint measure Markovian.
Janzing, Dominik, Schoelkopf, Bernhard
core +3 more sources
Claustrum Volume Is Reduced in Multiple Sclerosis and Predicts Disability
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective The claustrum is a small, thin structure of predominantly gray matter with broad connectivity and enigmatic function. Little is known regarding the impact of claustrum pathology in multiple sclerosis (MS). Methods This study assessed whether claustrum volume was reduced in MS and whether reductions were associated with specific ...
Nicole Shelley +5 more
wiley +1 more source