Results 81 to 90 of about 4,991,682 (267)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
EIRP Proceedings, 2009 One of the main contemporary reforms of the trading companies in Romania has been realized through Lawno. 441/2006, through which, besides the introduction of corporatist government principles, other legislations and otherconceptions of absolute novelty ...
Dragoş-Mihail Daghie
doaj
General Relativity and Gravitation, 2011 Forthcoming in General Relativity and ...
openaire +2 more sources
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Frontiers in Sustainable Food SystemsIndependent oil palm smallholders in Indonesia contributed significantly to the sustainable of Crude Palm Oil (CPO) supply chain. On the other hand, sustainability in the process of implementing the supply chain system for independent smallholders is an ...
Julian Witjaksono +10 more
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The price of independence [PDF]
BMJ, 2006 Career pressure and a focus on payment by results are making the critical and impartial thinker an endangered species. Society must take steps to protect this invaluable resource My professional life has been dominated by a drive to ensure that every opinion or piece of advice I give is independent and seen as such. Independence first became an issue
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FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
High-Quality Development Strategy of the Industrial Chain of Marine Equipment in China [PDF]
中国工程科学The industrial chain of marine equipment is extensive and complex, playing a vital role in ensuring the security of the marine economy. In China, part of the marine equipment market and orders are based abroad, and some of the core technologies and ...
Jie Zheng +4 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source