Results 71 to 80 of about 27,482,395 (244)

Identifying Rodent Resting-State Brain Networks with Independent Component Analysis

open access: yesFrontiers in Neuroscience, 2017
Rodent models have opened the door to a better understanding of the neurobiology of brain disorders and increased our ability to evaluate novel treatments.
Dusica Bajic   +12 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

An efficient quantum algorithm for independent component analysis

open access: yesNew Journal of Physics
Independent component analysis (ICA) is a fundamental data processing technique to decompose the captured signals into as independent as possible components.
Xiao-Fan Xu   +5 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Adaptive Complex-Valued Independent Component Analysis Based on Second-Order Statistics

open access: yesJournal of Electrical and Computer Engineering, 2016
This paper proposes a two-stage fast convergence adaptive complex-valued independent component analysis based on second-order statistics of complex-valued source signals. The first stage constructs a cost function by extending the real-valued whiten cost
Yanfei Jia, Xiaodong Yang
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Multidimensional Comparisons Between Constrained ICA/IVA Algorithms for Multi-Subject fMRI Data Analysis

open access: yesIEEE Access
Large-scale functional magnetic resonance imaging (fMRI) datasets provide exciting opportunities for understanding and improving brain health. Data-driven techniques such as independent component analysis (ICA) and independent vector analysis (IVA) have ...
Lucas Gois   +7 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Watermark Detection and Extraction Using Independent Component Analysis Method

open access: yesEURASIP Journal on Advances in Signal Processing, 2002
This paper proposes a new image watermarking technique, which adopts Independent Component Analysis (ICA) for watermark detection and extraction process (i.e., dewatermarking). Watermark embedding is performed in the spatial domain of the original image.
Yu Dan, Sattar Farook, Ma Kai-Kuang
doaj   +1 more source

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