Results 71 to 80 of about 525,941 (274)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Introducing the Center for Emerging Cultural Studies (Ecuador): Independent Research on Mythogenesis, Cultural Semiotics, and Living Heritage

open access: yes
This working paper inaugurates the Center for Emerging Cultural Studies (Ecuador), a field-based research initiative dedicated to analyzing contemporary mythogenesis, cultural semiotics, and heritage conflict in Latin America. Developed from more than a decade of empirical observation in Baños de Agua Santa, Ecuador, the Center investigates how ...
openaire   +2 more sources

Valuing Historic Places: Traditional and Contemporary Approaches [PDF]

open access: yes, 2010
Decisions about which older buildings, structures, and places should be conserved are fundamental to the practice of architectural conservation. Conservation professionals use the interrelated concepts of integrity, authenticity, and historical value to ...
Wells, Jeremy C.
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Hinking about art as work: self-management and new job opportunities for artists

open access: yesCuadernos de Antropología Social, 2017
Within circuits of dissemination, visibility and legitimacy of art that were structured in Argentina, there has been a trend by which metropolitan cities like Buenos Aires have condensed exhibition and marketing spaces with more recognition in this field,
Delfina Zarauza
doaj  

Coming Up Taller [PDF]

open access: yes, 2010
Coming Up Taller is a report filled with hope, a narrative about youth learning to paint, sing, write plays and poems, take photographs, make videos and play drums or violins.

core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Immigrant Youth and Digital Disparty in California [PDF]

open access: yes, 2006
This study addresses three key research questions regarding immigrant youth and the digital divide:What are the patterns of home technology use among native-born and immigrant families and youth?What are the causes and consequences of the digital divide ...
Rob Fairlie
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

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