Results 81 to 90 of about 525,941 (274)

Challenging Perceptions: Exploring the Relationship between ELL students and writing centers [PDF]

open access: yes, 2017
In an attempt to create more meaningful and effective assessment, the Howe Writing Center at Miami University implemented a new post-consultation/exit survey.
Cheatle, Joseph
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

SANTOS HISTORICAL CULTURAL CENTER WITH EXHIBITIONS IN HONOR OF THE PATRON OF BRAZILIAN INDEPENDENCE, JOSÉ BONIFÁCIO DE ANDRADA E SILVA

open access: yes
This paper presents an architectural project for a cultural center featuring permanent exhibitions in homage to José Bonifácio de Andrada e Silva, the patron of Brazilian independence. The facility is situated in the historic center of Santos, São Paulo, Brazil, on the site encompassing the Arcos do Valongo, a protected historic gable designated by the
Silva, João Pedro   +2 more
openaire   +1 more source

The Disruption of Taxi and Limousine Markets by Digital Platform Corporations in Western Europe and the United States: Responses of Business Associations, Labor Unions, and Other Interest Groups [PDF]

open access: yes, 2019
The entry of digital platform corporations, such as Uber, Lyft, and Taxify, into established taxi and limousine markets has severely challenged organized interest groups on both sides of the capital-labor divide as well as public policymakers who ...
Pernicka, Susanne
core  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Assessment of knowledge and attitudes towards safety events reporting among residents in a community health system

open access: yesJournal of Community Hospital Internal Medicine Perspectives, 2018
Background: Resident physicians are known to be infrequent reporters of patient safety events (PSE). Previous studies assessing barriers to resident PSE reporting have not considered possible cultural barriers faced by international medical graduates ...
M. Singal   +5 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Mapping Bozhou’s urban identity through multilingual media discourse: A big data study on the “World Capital of Traditional Chinese Medicine”

open access: yesNew Techno-Humanities
This study takes Bozhou City, the “World Capital of Traditional Chinese Medicine,” as a case study. Based on the Multilingual Big Data Platform of Beijing Language and Culture University, we analyze domestic and international media coverage related to ...
Xu Ming   +5 more
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

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