Results 101 to 110 of about 525,941 (274)

Pathways to Higher Education [PDF]

open access: yes, 2008
Presents case studies from Ford's initiative to support efforts to transform universities abroad to enable poor, minority, and otherwise underrepresented students to obtain a university degree.
Irma Rosa Martinez   +4 more
core  

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Exploring the Epistemology of Illicit Drugs [PDF]

open access: yes, 2015
In this essay I explore the epistemology of drugs in America. That is, how Americans come to know and define drugs and their users; and, in turn, how those definitions manifest in social institutions.
Linseman, Holly
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Slip-painted Pottery (Types, Widespread, Dating) [PDF]

open access: yesنگره, 2012
About two centuries after the appearance of Islam, the production of potteries were gradually changing through Islamic world. At eastern parts these changes were taking place coincident with Iranian movements and establishment of independent dynasties ...
Morteza Ataie   +2 more
doaj  

HELIN Consortium LORI Grant United States Online History_Digital Repository Sites [PDF]

open access: yes, 2014
Description of state online history,digital repository sites, repared by: Emily Cuellar and Thomas Evans, Rhode Island State Library, July ...

core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Human Security & Global Understanding: Towards New World Relations

open access: yesCadmus, 2023
The semantical as well as the practical implications of ‘human security’ need to be re-adapted due to the constantly changing kind of vulnerabilities of all people around the planet, independent of their place, culture, status or beliefs.
Benno Werlen
doaj  

Working Towards a Globalized Minority: Regional German-Kurdish Cultural Organizations and Transnational Networks

open access: yes, 2014
German-Kurdish cultural organizations and the Kurdish Diaspora they represent offer an example of a new type of actor in defining globalization. This paper examines how such organizations act as the lynchpin in transnational networks and how such ...
Hoffman, Drew A.
core  

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