Results 111 to 120 of about 7,147,780 (265)
Cost Management in Agribusiness: study profitability scenarios of Integrated System vs. Independent System for a Poultry Producer. [PDF]
, 2014 Addressing the theme of the cost management in agribusiness poultry industry, this study aims to analyze from the perspective of variable costing indicators the possibility of a poultry producer who works under the scheme of integration migrate to a ...
Wanzeler, Maritiza dos Santos +3 more
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Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
SİYASAL-SOSYAL GÖRÜŞLERİ VE DİNİ YÖNÜYLE AFGANİ1 (Son Bir Umut: İslam Birliği)
İslami İlimler Dergisi, 2008 As a religious scholar, al-Afghani, who is the most prominent Pan-Islamist figure of the modern history of Islam with a robust anti-imperialistic stance, has been a subject of controversy in terms of his life, personality, nationality and school of ...
Muammer Esen
doaj
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Ohio Cultural Facilities Commission legislative resource guide
, 2007 Ed. 3.0.; Title from PDF cover (viewed on Feb. 13, 2008).; "January 2007."; Harvested from the web on 2/13/08Introduction -- Why the state should invest in community capital projects -- How projects secure funding -- Commission role & responsibilities --
Ohio Cultural Facilities Commission.
core
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source