Results 71 to 80 of about 8,468 (237)

On k-rainbow independent domination in graphs [PDF]

Applied Mathematics and Computation, 2018
16 pages, 2 figures, 18 ...
Kraner Šumenjak, Tadeja, Rall, Douglas F., Tepeh, Aleksandra   +2 more
openaire   +3 more sources

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Strong Equality Between the Roman Domination and Independent Roman Domination Numbers in Trees

Discussiones Mathematicae Graph Theory, 2013
A Roman dominating function (RDF) on a graph G = (V,E) is a function f : V −→ {0, 1, 2} satisfying the condition that every vertex u for which f(u) = 0 is adjacent to at least one vertex v for which f(v) = 2.
Chellali Mustapha, Rad Nader Jafari
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Outer independent total double Italian domination number [PDF]

Computer Science Journal of Moldova
If $G$ is a graph with vertex set $V(G)$, then let $N[u]$ be the closed neighborhood of the vertex $u\in V(G)$. A total double Italian dominating function (TDIDF) on a graph $G$ is a function $f:V(G)\rightarrow\{0,1,2,3\}$ satisfying (i) $f(N[u])\ge 3 ...
Seyed Mahmoud Sheikholeslami, Lutz Volkmann   +1 more
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Independent Domination Stable Trees and Unicyclic Graphs

Mathematics, 2019
A set S ⊆ V ( G ) in a graph G is a dominating set if S dominates all vertices in G, where we say a vertex dominates each vertex in its closed neighbourhood. A set is independent if it is pairwise non-adjacent.
Pu Wu, Huiqin Jiang, Sakineh Nazari-Moghaddam, Seyed Mahmoud Sheikholeslami, Zehui Shao, Lutz Volkmann   +5 more
doaj   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

A note on Fibonacci and Lucas number of domination in path

Electronic Journal of Graph Theory and Applications, 2018
Let G = (V(G), E(G)) be a path of order n ≥ 1. Let fm(G) be a path with m ≥ 0 independent dominating vertices which follows a Fibonacci string of binary numbers where 1 is the dominating vertex.
Leomarich F Casinillo
doaj   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source