Results 151 to 160 of about 3,030,309 (307)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Promoting Self-Management and Independent Living of Older Individuals with Chronic Diseases through Technology: A Study of Self-Reported Needs, Priorities, and Preferences. [PDF]

Medicina (Kaunas), 2023
Kalaitzaki A, Rovithis M, Dimitropoulos A, Koukouli S, Linardakis M, Katsiri E, Rikos N, Vasilopoulos G, Tsolas G, Papachristou A, Dimitrantzou A, Katsiris D, Stavropoulou A.   +12 more
europepmc   +1 more source

Reforming Youth Allowance: The “Independent-at- Home” Category [PDF]

Several of the Youth Allowance eligibility criteria for independent status were subject to severe criticism in the recent Review of Australian Higher Education (2008).
Bruce Chapman, Kiatanantha Lounkaew
core  

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Family perspectives on independent living for adults with cerebral palsy: barriers, support needs, and quality of life. [PDF]

Front Psychiatry
Aguayo V, Esteban L, García-Domínguez L, Verdugo MA.   +3 more
europepmc   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Independent living transitions for young people with cerebral palsy in Australia: aligning policy and practice with family realities. [PDF]

Front Public Health
Hickey L, Nguyen HTD, Harms L, Culnane E, Saunders V, Imms C, Ball M, Reddihough D.   +7 more
europepmc   +1 more source

Assessing Older Adults' Decision-Making Capacity for Independent Living: Practice Tensions and Complexities. [PDF]

J Appl Gerontol, 2022
Usher R, Stapleton T.
europepmc   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Aging in Place or Institutionalization? A Multiscale Analysis of Independent-Living Older Adults From Four Large Cities in China's Yangtze River Delta. [PDF]

Innov Aging, 2023
He Z, Jiang C.
europepmc   +1 more source