Results 151 to 160 of about 6,147,251 (299)

Factors of Parental Preparation of Children with Mental Illnesses for Their Independent Living after Their Own Death. [PDF]

Healthcare (Basel), 2022
Yoshioka-Maeda K, Fujii H, Kageyama M, Takamura S.   +3 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Family perspectives on independent living for adults with cerebral palsy: barriers, support needs, and quality of life. [PDF]

Front Psychiatry
Aguayo V, Esteban L, García-Domínguez L, Verdugo MA.   +3 more
europepmc   +1 more source

Challenging "The Hands of Technology": An Analysis of Independent Living for People with Intellectual Disabilities. [PDF]

Int J Environ Res Public Health, 2022
Moyà-Köhler J, Domènech M.
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Chain mediation analysis of fall risk and independent living skills in patients with acute ischemic stroke between cognitive dysfunction and frailty. [PDF]

Medicine (Baltimore)
Yang J, Liu S, He Y, Zhang Y, Niu Y, Sun H, Tai J, Zhao Z, Cui W, Yin Y, Li K, Sun H.   +11 more
europepmc   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Independent living transitions for young people with cerebral palsy in Australia: aligning policy and practice with family realities. [PDF]

Front Public Health
Hickey L, Nguyen HTD, Harms L, Culnane E, Saunders V, Imms C, Ball M, Reddihough D.   +7 more
europepmc   +1 more source

Complex interventions for improving independent living and quality of life amongst community-dwelling older adults: a systematic review and meta-analysis. [PDF]

Age Ageing, 2023
Ho L, Malden S, McGill K, Shimonovich M, Frost H, Aujla N, Ho IS, Shenkin SD, Hanratty B, Mercer SW, Guthrie B.   +10 more
europepmc   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source