Results 101 to 110 of about 4,267,953 (306)

Effective Dark Matter Model: Relic density, CDMS II, Fermi LAT and LHC

open access: yes, 2011
The Cryogenic Dark Matter Search recently announced the observation of two signal events with a 77% confidence level. Although statistically inconclusive, it is nevertheless suggestive.
A Birkedal   +81 more
core   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

A feature fusion based forecasting model for financial time series. [PDF]

open access: yesPLoS ONE, 2014
Predicting the stock market has become an increasingly interesting research area for both researchers and investors, and many prediction models have been proposed.
Zhiqiang Guo   +3 more
doaj   +1 more source

Non-perturbative renormalization of overlap quark bilinears on domain wall fermion configurations [PDF]

open access: yes, 2013
We present renormalization constants of overlap quark bilinear operators on 2+1-flavor domain wall fermion configurations. Both overlap and domain wall fermions have chiral symmetry on the lattice.
Chen, Ying   +8 more
core  

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

News Schemes for Activity Recognition Systems Using PCA-WSVM, ICA-WSVM, and LDA-WSVM

open access: yesInformation, 2015
Feature extraction and classification are two key steps for activity recognition in a smart home environment. In this work, we used three methods for feature extraction: Principal Component Analysis (PCA), Independent Component Analysis (ICA), and Linear
M’hamed Bilal Abidine   +1 more
doaj   +1 more source

A Hybrid Heuristic Dimensionality Reduction Methods for Classifying Malaria Vector Gene Expression Data

open access: yesIEEE Access, 2020
Malaria is the world's leading cause of death, spread by Anopheles mosquitoes. Gene expression is a fundamental level where the effects of unseen vital revealing genes and developmental systems can be evident for detection of distinctions in malaria ...
Micheal O. Arowolo   +3 more
doaj   +1 more source

Mean field limit of interacting filaments and vector valued non linear PDEs

open access: yes, 2016
Families of $N$ interacting curves are considered, with long range, mean field type, interaction. A family of curves defines a 1-current, concentrated on the curves, analog of the empirical measure of interacting point particles.
Bessaih, Hakima   +2 more
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

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