Results 41 to 50 of about 4,922,335 (121)

Erdheim‐Chester disease associated with myeloid neoplasm: Clinical features, molecular landscape, and treatment outcomes

HemaSphere, Volume 10, Issue 4, April 2026.
Abstract Erdheim‐Chester disease (ECD) is frequently associated with clonal hematopoiesis and myeloid neoplasms (MN), but clinical phenotype and response to kinase inhibitors (KI) in this setting remain unclear. We analyzed 67 patients with ECD associated with MN (ECD‐MN) from a French national cohort and assessed ECD treatment response, MN progression,
Ambroise Le Pogam, Matthias Papo, Pierre Hirsch, Fleur Cohen‐Aubart, Jean‐François Emile, François Delhommeau, Pierre Duffau, Jérôme Razanamahery, Florence Nguyen‐Khac, Christopher Nunes Gomes, Felicien Triboulet, Jeanne de La Rochefoucauld, Chloé McAvoy, Estibaliz Lazaro, Mehdi Hage‐Sleiman, Damien Roos‐Weil, François Chasset, Vincent Jachiet, Arsène Mekinian, Olivier Fain, Zahir Amoura, Jérôme Hadjadj, Julien Haroche   +22 more
wiley   +1 more source

Novel BRAF fusion in Erdheim–Chester disease with pulmonary manifestations: Importance of RNA‐based testing and response to MEK inhibition

Histopathology, Volume 89, Issue 3, Page 558-561, September 2026.
Igor Odintsov, Henry D. Tazelaar, Jerry C. Lee, Lloyd E. Damon, Walter Patrick Devine, Kirk D. Jones   +5 more
wiley   +1 more source

Challenges and Strategies in Managing Pulmonary Arterial Hypertension Within the Indian Healthcare System: A Consensus Statement From the Pulmonary Vascular Research Institute India Taskforce

Pulmonary Circulation, Volume 16, Issue 2, April 2026.
ABSTRACT Pulmonary arterial hypertension (PAH) in India is a substantial yet under‐recognized contributor to cardiovascular morbidity and mortality. Its progressive course, nonspecific early manifestations, and heterogeneous aetiologies often lead to delayed diagnosis and fragmented care.
Prashant Bobhate, Neeraj Awasthy, Abraham Samuel Babu, Shatabdi Giri, Arun Gopalakrishnan, Sivadasanpillai Harikrishnan, Niharikar Karandikar, Basha J. Khan, Snehal Kulkarni, Shine Kumar, Rahul Mehrotra, Smrutiranjan Mohanty, S. Ramakrishnan, Anita Saxena, Padmanabha Shenoy, B. K. Srinivasa Sastry, T. Sunder   +16 more
wiley   +1 more source

A bHLH Complex Controls Embryonic Vascular Tissue Establishment and Indeterminate Growth in Arabidopsis [PDF]

, 2013
Plants have a remarkable potential for sustained (indeterminate) postembryonic growth. Following their specification in the early embryo, tissue-specific precursor cells first establish tissues and later maintain them postembryonically.
Barbier de Reuille, Pierre, Boeren, Sjef, Grabowicz, Ilona, Smith, R.S., Barbier de Reuille, P., Boeren, S., Borst, J.W., Yoshida, Saiko, Smith, Richard S., Weijers, Dolf, Weijers, D., Möller, Barbara, Moller, B.K., De Rybel, Bert, Smith, Richard Simon, De Rybel, B., Yoshida, S., Smith, Richard S, Rybel, B., De, Grabowicz, I., Borst, Jan Willem   +20 more
core   +2 more sources

Frequent NPM1 mutation, monoblastic/monocytic origin and prognostic significance of organ and system involvement in myeloid sarcoma: a multicenter study

The Journal of Pathology: Clinical Research, Volume 12, Issue 2, March 2026.
Abstract Myeloid sarcoma (MS) is a tumorous extramedullary proliferation of blast or blast equivalent cells (e.g., promonocytes or promyelocytes). The most frequent cutaneous presentation is often referred to as leukemia cutis (LC). These lesions, especially without the clinical context of a known bone marrow disease, pose a differential diagnostic ...
Alex Jenei, Béla Kajtár, Tamás László, Hazem A Juratli, Livia Vida, Ágota Szepesi, Réka Mózes, Botond Timár, Jörg Halter, Stefan Dirnhofer, Alexandar Tzankov   +10 more
wiley   +1 more source

Ethical considerations of genetic and genomic testing in pediatric oncology: A narrative review

CA: A Cancer Journal for Clinicians, Volume 76, Issue 2, March/April 2026.
Abstract Genomics—and genomic testing in particular—has transformed oncology, facilitating both targeted therapies and personalized care. In pediatric oncology, unique clinical and ethical considerations arise. Compared with adults, children and adolescents are affected by more limited evidence regarding test performance, variant interpretation, and ...
Brittany L. Greene, Jonathan M. Marron
wiley   +1 more source

A Rare Cause of Proptosis in Childhood: Langerhans Cell Histiocytosis

, 2016
A three-year-old male patient was admitted to the clinic with proptosis in his right eye. He had a history of fever with an unknown etiology. In examination, right proptosis was observed and an immobile mass was palpated at the lateral wall of the right ...
Esra Vatansever, Ayça Sarı, Tuba Kara, Mustafa Vatansever, Erdem Dinç   +4 more
core   +1 more source

Langerhans cell histiocytosis of liver [PDF]

, 2020
Langerhans cell histiocytosis (LCH) is a rare disorder of unknown etiology caused by proliferation of Langerhans cells. It can involve single organ system to multi organ systems and clinical presentation is variable depending on the organ involved and ...
Patodiya, Bharat, Duvuru, Nageshwar Reddy, Samudrala, Swapna, Sekaran, Anuradha   +3 more
core   +1 more source

WHO classification of skin tumours: key updates in the fifth edition

Histopathology, Volume 88, Issue 3, Page 555-568, February 2026.
This review article summarizes the key updates in the 5th edition of the WHO Classification of Skin Tumours. It provides an overview of the major changes and new entities specific to the skin section, covering areas such as epidermal, melanocytic, mesenchymal and other tumours. The 5th edition of the World Health Organization Classification of Tumours (
Gabrielle Goldman‐Lévy, Raymond Barnhill, Boris C. Bastian, Werner Kempf, David Elder, Pedram Gerami, Wayne Grayson, Dmitry Kazakov, Daniela Massi, Jane Messina, Arnaud de la Fouchardière, Alexander J. Lazar, Thomas Brenn, Brian Rous, Andrew Field, Anthony Gill, Jennelle C. Hodge, Joseph D Khoury, Katia Leite, Shahin Sayed, Puay Hoon Tan, Rosalie Elenitsas, Eduardo Calonje, Lyn M. Duncan, Liang Zhiyong, Holger Moch, Rajendra Singh, Harshima Wijesinghe, Ian Cree, Dilani Lokuhetty   +29 more
wiley   +1 more source

Langerhans cell histiocytosis (histiocytosis X) [PDF]

, 1997
There has been a renewed interest in Langerhans cell histiocytosis in recent years due both to advances in basic research and to improvements in diagnostic and treatment approaches.
K Y Lam, Lam, KY
core   +1 more source