Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
The negative association between C-reactive protein-albumin-lymphocyte index and cardiovascular disease. [PDF]
Chen S, Lin M, Ye J.
europepmc +1 more source
Comparison Of Body Mass Index (BMI), an old modality for prediction of gestational diabetes, with the new formulas such as Body Adipose Index (BAİ), Adipose Percentage and Type a Body Fat Index (ABSI): a prospective cohort study. [PDF]
Bozkurt Ozdal B +7 more
europepmc +1 more source
Impact of TyG index on coronary plaques in patients with coronary artery disease under aggressive lipid-lowering therapy. [PDF]
Fukase T +9 more
europepmc +1 more source
Prediction of Pregnancy-Related Complications in Women of Advanced Maternal Age: A Nomogram Based on LASSO and Logistic Regression. [PDF]
Guo F, Fang H, Sun Z, Huo G, Cui Y.
europepmc +1 more source
Intrathecal immunoglobulin production in the diagnosis, prognosis, and monitoring of autoimmune diseases of the central nervous system. [PDF]
Renaudineau Y, Puissant-Lubrano B.
europepmc +1 more source

