Results 41 to 50 of about 5,830,351 (259)

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Comparative study on the fire-extinguishing effectiveness of N2 and CO2 on coal flame combustion

open access: yes矿业科学学报, 2017
In order to master thoroughly the different fire-extinguishing effects of N2 and CO2 on coal flame combustion, the self-developed experiment device of coal flame combustion was used to conduct the fire-extinguishing experiment on coal flame combustion ...
Guo Zhiguo, Wu Bing
doaj  

The Main Controlling Factors and Evaluation Method of the Reservoir Stimulation Potential: A Case Study of the Changning Shale Gas Field, Southern Sichuan Basin, SW China

open access: yesFrontiers in Earth Science, 2021
Based on logging, seismic, fracturing and production data from 301 productive wells in Longmaxi Formation in Changning shale gas field of southern Sichuan basin, the various influence factors of shale gas stimulated potential have been analyzed to carry ...
Cheng Shen   +5 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

Dual-Core Fiber-Based Interferometer for Detection of Gas Refractive Index

open access: yesPhotonics, 2020
We demonstrate a dual-core fiber-based Mach–Zehnder interferometer that could be used for precise detection of variations in refractive indices of gaseous samples.
Haijin Chen   +7 more
doaj   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

open access: yesFEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta   +7 more
wiley   +1 more source

Gas Chromatographic Retention Index Prediction Using Multimodal Machine Learning

open access: yesIEEE Access, 2020
Gas chromatography is a widely used method in analytical chemistry and metabolomics. Using gas chromatography, vaporizable compounds can be separated for their further identification.
Dmitriy D. Matyushin, Aleksey K. Buryak
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

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