Results 231 to 240 of about 5,997,708 (388)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Comparison between the modelled and measured refractive index modulation within a FBG

Betty Kouskousis, Nicoleta Dragomir, Claire M. Rollinson, Scott A. Wade, Stephen F Collins, G. W. Baxter, Ann Roberts   +6 more
openalex   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Electrically Tunable Optofluidic Metasurface. [PDF]

ACS Nano
Blair SFJ, Khan M, Reardon CP, Johnson S, Krauss TF.   +4 more
europepmc   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Polarization-Insensitive Electro-Optic Modulator for the Terahertz Regime Enabled by a Graphene-Hybrid Plasmonic Waveguide. [PDF]

Nanomaterials (Basel)
Zhou X, Liu C, Li Y, Weng T, Tan Q, Huang X, Pan J.   +6 more
europepmc   +1 more source

Referee report. For: Positive or negative allosteric modulation of metabotropic glutamate receptor 5 (mGluR5) does not alter expression of behavioral sensitization to methamphetamine [v1; indexed, http://f1000r.es/o0]

, 2013
David J. Triggle
openalex   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Exploring Nociceptive-Analgesic Balance and EEG Modulation Patterns During General Anesthesia Using Holo-Hilbert Spectral Analysis. [PDF]

Pain Res Manag
Ho CN, Huang NE, Chen JY, Yang AC.
europepmc   +1 more source

Running spectral index from large-field inflation with modulations revisited

, 2014
Michael Czerny, Takeshi Kobayashi, Fuminobu Takahashi   +2 more
openalex   +1 more source