Results 41 to 50 of about 7,904 (250)

Aptamer‐Directed Porous DNA Nanocomposite Hydrogel for Active Pulp Preservation: Immunomodulation, Stem Cell Recruitment and Reparative Dentinogenesis

Advanced Science, EarlyView.
This study presents an injectable DNA‐based porous hydrogel integrating catechol motifs and targeting aptamers for pulpitis management. Upon in situ crosslinking, the scaffold actively recruits endogenous dental pulp stem cells, restores redox homeostasis, and modulates immune responses.
Luhui Cai, Huan Yu, Zihan Ni, Kan Chen, I‐Chen Tsai, Zeyu Bao, Shuo Sun, Weichang Li, Yunhua Chen, Qiong Xu   +9 more
wiley   +1 more source

The prevalence of malocclusions in patients seeking orthodontic treatment at COMS from Chitwan District of Nepal

Orthodontic Journal of Nepal, 2023
Background: Malocclusion is the abnormal relation between maxillary and mandibular teeth which leads to various problems like esthetics, phonation, mastication, psychological and social problems. The prevalence of malocclusion is highly variable and its
Kanistika Jha, Manoj Adhikari
doaj   +1 more source

PDGFRα+/Integrin α2+ Fibroblasts Orchestrate Tumor Budding in Oral Squamous Cell Carcinoma via Mechano‐Metabolic Symbiosis: E‐Cadherin/Integrin α2β1 Adhesion and Mitochondrial Transfer

Advanced Science, EarlyView.
PDGFA/PDGFRα signaling recruits CAFs to OSCC nests, and CAF‐OSCC contact drives tumor budding invasion. Mechanistically, heterotypic adhesion via E‐cadherin/integrin α2β1 activates YAP signaling in OSCC cells, inducing EMT. Concurrently, CAFs transfer mitochondria through TNTs, supplying ATP to fuel invasion.
Yufang Liu, Jiao Li, Juan Liu, Qi Dong, Haoyang Zhang, Yanjin Wang, Huibing Li, Ye Guan, Lei Cao, Manqing Zhang, Fangning Guo, Xue Liu, Zhen Yang, Mengmeng Lu, Hui Liu, Laiping Zhong, Tong Ji, Tingjiao Liu   +17 more
wiley   +1 more source

Self-perceived need for dental treatment and related factors. A cross-sectional population-based study

Brazilian Oral Research, 2016
This study compared adolescents’ self-perceived need for orthodontic treatment with the normative need for such treatment and investigated associations between socioeconomic and demographic variables and self-perceptions of dental malocclusion.
Luciana Freitas Gomes e SILVA, Erika Barbara Abreu Fonseca THOMAZ, Heloiza Viana FREITAS, Cecília Cláudia Costa RIBEIRO, Alex Luiz Pozzobon PEREIRA, Cláudia Maria Coelho ALVES   +5 more
doaj   +1 more source

Comparing orthodontic treatment need indexes

, 2008
Background: Orthodontic Treatment Need Indexes are investigated to evaluate their validity criteria and their formulation on a scientific basis. Methods: A bibliographic research was performed on Medline Database to find articles about orthodontic treatment need indexes published from 1960 to 2007. English language papers about criteria to establish
Grippaudo, Cristina, Paolantonio, Ester Giulia, La Torre, Giuseppe, Gualano, Maria Rosaria, Oliva, Bruno, Deli, Roberto   +5 more
openaire   +2 more sources

Index of orthodontic treatment need in children from the Nis region

Vojnosanitetski pregled, 2015
Background/Aim. The Index of Orthodontic Treatment Need (IOTN) is a scoring system for malocclusion that consists of the two independent components: Denal Health Component (DHC) and Aesthetic Component (AC). IOTNs are usually used in the countries with dental healthcare financed by the government through the national healthcare system or ...
Janošević Predrag, Stošić Maja, Janošević Mirjana, Radojičić Julija, Filipović Gordana, Čutović Tatjana   +5 more
openaire   +3 more sources

The use of the Index of Orthodontic Treatment Need in dental primary care [PDF]

British Dental Journal, 2009
The primary objective of this survey was to assess the use of the Index of Orthodontic Treatment Need (IOTN) in dental primary care (Scottish general dental services - SGDS), and to compare orthodontic specialists (OS) and general dental practitioners (GDPs).
Ho-A-Yun, J., Crawford, F., Clarkson, J.
openaire   +3 more sources

Animal models in molecular biology research: Challenges, ethical imperatives, and the path to human‐relevant translation

Animal Models and Experimental Medicine, EarlyView.
The graphical abstract shows how molecular biology research has shifted from using traditional animal models toward using methods that are more relevant to humans. It points out the main problems, differences between species, difficulty in reproducing results, moral issues, and lack of infrastructure that make translational accuracy harder to achieve ...
Md. Shajid Hossain Rafi, Md. Taslim Sarker, Ferdous‐Ul‐Haque Joy, Shahriar Mohd Shams, Tahmina Foyez, Md. Abdul Mazid, Syed Masudur Rahman Dewan   +6 more
wiley   +1 more source

Cortical bone distribution in the human mandibular symphysis: Ontogenic and morphometric approaches in archeological context

The Anatomical Record, EarlyView.
Abstract The human mandibular symphysis concentrates multiaxial loads during function and remodels throughout growth, but the precise mechanisms underlying cortical bone shape during growth remain relatively unexplored. Approaches based solely on thickness or external cortical contours provide only partial insights and do not capture the functional ...
Ana Ribeiro, Elsa Garot, Christine Couture, Pierre‐Hadrien Decaup   +3 more
wiley   +1 more source

Management of severe bone loss in patients at risk of medication‐related osteonecrosis of the jaw with microsurgery and guided bone regeneration: A case study

Clinical Advances in Periodontics, EarlyView.
Abstract Background Medication‐related osteonecrosis of the jaw (MRONJ) is a challenging complication associated with antiresorptive medications. Its exact pathophysiology remains unclear, but dental extractions and infections are known triggers, complicating prevention, and treatment.
Pedro Franco Ferreira, José Maurício Paradella de Camargo, Lara Maria Alencar Ramos Innocentini, Ana Carolina Fragoso Motta   +3 more
wiley   +1 more source