Results 51 to 60 of about 18,944 (299)

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Evaluation of Association between Body Dysmorphic Disorder with the Aesthetic Component of the Index of Orthodontic Treatment Need from the Perspective of Patient and Orthodontists [PDF]

Journal of Mashhad Dental School
Background: Body dysmorphic disorder is a psychological condition in which an individual persistently focuses on minor or imperceptible flaws in their appearance. This disorder has a high prevalence among orthodontic patients and can affect the patient's
Houriyeh Khatami, Meisam Moradi, Reza Faraji, Manouchehr Rahmati Kamel, Seyedali Seyedmajidi, Mahjoubeh Betyar   +5 more
doaj   +1 more source

Occlusal outcomes in combined orthodontic and orthognathic treatment [PDF]

, 2017
OBJECTIVE: To investigate the treatment outcome in terms of the malocclusion features and the changes in the occlusion of patients undergoing orthodontic/orthognathic treatment using the Peer Assessment Rating (PAR) and the Index of Complexity, Outcome ...
Almutairi, F, Hodges, SJ, Hunt, NP
core  

Treatment of dental complications in sickle cell disease. [PDF]

, 2016
BACKGROUND: Sickle cell disease is the most common single gene disorder and the commonest haemoglobinopathy found with high prevalence in many populations across the world.
Abas, Adinegara B L, Ballas, Samir K., Karanth, Laxminarayan, Mulimani, Priti   +3 more
core   +2 more sources

Multi‐Enzyme Mimetic Molybdenum Nitride Nanozymes Reshape Subgingival Microenvironment for Synergistic Periodontitis Therapy via ROS Regulation and Microbiome Remodeling

Advanced Science, EarlyView.
ABSTRACT Periodontitis, a chronic inflammatory disease initiated and sustained by plaque microorganisms and host immune response, remains an intractable oral disease and a leading cause of tooth loss worldwide. Traditional mechanical debridement and adjunctive antibiotic or antiseptic therapy often shows limited efficacy due to the complex anatomical ...
Weiyu Zhang, Zhongwei Yang, Yunfan Zhang, Longwei Wang, Xiaoyu Zhang, Jiahui Mao, Yizhi Dai, Yifan Yuan, Mingge Wang, Xin Yang, Xin Yu, Jing Liu, Chunying Chen   +12 more
wiley   +1 more source

Index of orthodontic treatment need in children from the Nis region

Vojnosanitetski pregled, 2015
Background/Aim. The Index of Orthodontic Treatment Need (IOTN) is a scoring system for malocclusion that consists of the two independent components: Denal Health Component (DHC) and Aesthetic Component (AC). IOTNs are usually used in the countries with dental healthcare financed by the government through the national healthcare system or ...
Janošević Predrag, Stošić Maja, Janošević Mirjana, Radojičić Julija, Filipović Gordana, Čutović Tatjana   +5 more
openaire   +3 more sources

Myeloid‐Derived Grancalcin Promotes Periodontal Inflammation and Pathological Bone Remodeling in Periodontitis

Advanced Science, EarlyView.
Grancalcin (GCA), a myeloid‐derived protein, is enriched in gingival tissues of periodontitis patients and mouse models. Through interactions with CD44 and activation of MYH9, GCA promotes NF‐κB signaling and exacerbates periodontal inflammation and bone loss.
Min Zhou, Yao Xiao, Ziyue Xu, Chengyu Yang, Jiang Li, Ya Liu, Ping Yin   +6 more
wiley   +1 more source

Self-perceived need for dental treatment and related factors. A cross-sectional population-based study

Brazilian Oral Research, 2016
This study compared adolescents’ self-perceived need for orthodontic treatment with the normative need for such treatment and investigated associations between socioeconomic and demographic variables and self-perceptions of dental malocclusion.
Luciana Freitas Gomes e SILVA, Erika Barbara Abreu Fonseca THOMAZ, Heloiza Viana FREITAS, Cecília Cláudia Costa RIBEIRO, Alex Luiz Pozzobon PEREIRA, Cláudia Maria Coelho ALVES   +5 more
doaj   +1 more source

Orthodontic treatment need and prevalence of malocclusions in the Orthodontic Unit of "Sapienza - University of Rome" : a six - year clinical experience [PDF]

, 2019
AIM The objective of this epidemiological survey was to investigate the dental-skeletal features of subjects attending the Public Dental Service in U.O.C. (Orthodontic Department of “La Sapienza University of Rome) and compare them with the existing body
Giordano, Alessandra
core  

Comparison of two different debonding techniques in orthodontic treatment [PDF]

, 2017
The purpose of this research is to investigate whether and how the adhesive bond failure site varied in relation to the material used for the orthodontic bonding and debonding technique ...
Besharat, Laith Konstantinos, Di Carlo, Stefano, Di Giorgio, Roberto, Migliau, Guido, Piccoli, Luca, Pompa, Giorgio   +5 more
core   +1 more source