Results 71 to 80 of about 1,230,533 (309)

Structator: fast index-based search for RNA sequence-structure patterns

BMC Bioinformatics, 2011
Background The secondary structure of RNA molecules is intimately related to their function and often more conserved than the sequence. Hence, the important task of searching databases for RNAs requires to match sequence-structure patterns. Unfortunately,
Will Sebastian, Backofen Rolf, Kurtz Stefan, Meyer Fernando, Beckstette Michael   +4 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Refractive index change in a double quantum dot structure

Results in Optics
The density matrix theory models the refractive index change in a double quantum dot (DQD) system. The orthogonalized plane wave (OPW) is considered for wetting layer (WL)-quantum dot (QD) transitions, and the transition momenta are calculated.
Suha Hadi, Mohammed A.A. Abbas, Faten K. Hachim, Baqer Obaid Al-Nashy, Amin H. Al‑Khursan   +4 more
doaj   +1 more source

Application of quantitative structure property relationship to the design of high refractive index 193i resist [PDF]

, 2008
A robust quantitative structure property relationship (QSPR) model with five parameters has been developed from 126 organic compounds for the prediction of refractive index at 589 nm.
Conley, Willard, Whittaker, Andrew, Hill, David J. T., Hill, David, Conley, Willard E., Graeme George, Liu, Heping, George, Graeme, Blakey, Idriss, Whittaker, Andrew K.   +9 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Tariff index theory [PDF]

For a single tariff, the height of the tariff is an unambiguous measure of the policy's restrictiveness. With more than one tariff, theory has not provided an extension that captures the idea of the tariff's height, so analysts have used index numbers ...
Anderson, James E.
core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

The mechanical and clinical influences of prosthetic index structure in Morse taper implant-abutment connection: a scoping review. [PDF]

BMC Oral Health, 2023
Shen L, Dong C, Chen J, Bai X, Yang F, Wang L.   +5 more
europepmc   +1 more source

Estimation of Single-Index Models Based on Boosting Techniques [PDF]

, 2008
In single-index models the link or response function is not considered as fixed. The data determine the form of the unknown link function. In order to obtain a flexible form of the link function we specify the link function as an expansion in basis ...
Leitenstorfer, Florian, Tutz, Gerhard
core   +1 more source