Results 1 to 10 of about 70,706 (175)

Inhibiting FAT1 Blocks Metabolic Bypass to Enhance Antitumor Efficacy of TCA Cycle Inhibition through Suppressing CPT1A‐Dependent Fatty Acid Oxidation

open access: yesAdvanced Science, EarlyView.
This study demonstrates that mutant FAT1 promotes ASCL2‐driven, CPT1A‐dependent fatty acid oxidation, leading to resistance to CPI‐613‐mediated TCA cycle inhibition in head and neck cancer. In vivo gene depletion of mutant FAT1 with LNP‐sgFAT1 suppresses tumor growth and restores CPI‐613 sensitivity, revealing a targetable metabolic bypass with ...
Fanghui Chen   +11 more
wiley   +1 more source

Unveiling the Materiality of 19th Century's Color Spaces

open access: yesColor Research &Application, EarlyView.
ABSTRACT Several color theories flourished during the 19th century, marked by experiments on the distinction between color‐light and color‐matter. This study aims to compare the color plates designed to illustrate three of these color theories, namely M.E. Chevreul's chromatic circle (1861), O. Rood's frontispiece (1879), and C.
Aurore Malmert   +3 more
wiley   +1 more source

Saxifraga rufescens var. rufescens (Saxifragaceae): A New Addition to the Flora of India

open access: yesFeddes Repertorium, EarlyView.
ABSTRACT Saxifraga rufescens Balf.f., a species of Saxifragaceae, previously known from China and Myanmar, is now recorded from Nagaland, India. This study offers detailed morphological descriptions, habitat characteristics, field photographs, distributional data, and an analysis of its taxonomic relationships with closely related species, facilitating
Santanu Dey   +4 more
wiley   +1 more source

Accuracy of ultrasound estimation of fetal weight in twin pregnancy

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To determine the accuracy of formulas for estimation of fetal weight in twin pregnancy. Methods Inclusion criteria from the ESPRiT twin cohort were twin pregnancies that resulted in live‐born twins without congenital anomalies or twin‐twin transfusion syndrome, ultrasound examination within 3 days of delivery, birth weight (BW) > 500 
Patrick Dicker   +8 more
wiley   +1 more source

Platinum Group Element Traces of CAMP Volcanism Associated With Low‐Latitude Environmental and Biological Disruptions

open access: yesGeophysical Monograph Series, Page 263-304., 2021

Exploring the links between Large Igneous Provinces and dramatic environmental impact

An emerging consensus suggests that Large Igneous Provinces (LIPs) and Silicic LIPs (SLIPs) are a significant driver of dramatic global environmental and biological changes, including mass extinctions.
Jessica H. Whiteside   +3 more
wiley  

+1 more source

Meta‐regression of the relationship between dietary 18C n‐3 concentration and enrichment of n‐3 fatty acids in liver and breast muscle of broiler chickens

open access: yesLipids, EarlyView.
Abstract The long‐chain n‐3 fatty acids (FA) eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) have human health benefits, and many experiments have investigated the ability of plant n‐3 sources to enrich n‐3 FA in broiler meat. A meta‐regression was conducted to evaluate the relationship between dietary 18‐carbon n‐3 FA content and the ...
Usman Ali   +2 more
wiley   +1 more source

Photonic Floquet–Bloch Oscillations Dominated by Floquet Gauge

open access: yesLaser &Photonics Reviews, EarlyView.
A new type of Bloch oscillations (namely, asymmetric Floquet–Bloch oscillations) whose evolution is biased along the evolution dimension is proposed and visually observed. The Floquet gauge can determine the light broadening to be biased toward the first or second half of the period. These findings reveal a new mechanism for wave packet revival and may
Yuan Li   +4 more
wiley   +1 more source

Natural Language Processing Algorithms to Improve Digital Marketing Data Quality and Its Ethical Implications

open access: yesPsychology &Marketing, EarlyView.
ABSTRACT The ethical implications of personalization in digital marketing are significantly greater when companies adapt their marketing actions to individual consumer preferences. While this approach helps to reduce oversaturation and a sense of irrelevance among consumers, it also raises concerns about privacy and potential algorithmic bias. One form
Sergi Pons   +3 more
wiley   +1 more source

Corrections of Electron–Phonon Coupling for Second‐Order Structural Phase Transitions

open access: yesphysica status solidi (b), EarlyView.
The left image illustrates a weak electron–phonon coupling, while the right image depicts a strong electron–phonon coupling. The weak electron–phonon coupling interaction between the lattice and electrons is susceptible to destabilization by an increase in temperature.
Mario Graml, Kurt Hingerl
wiley   +1 more source

A Programming Platform Design for Children to Create and Explore Hybrid Musical Instruments

open access: yesSoftware: Practice and Experience, EarlyView.
ABSTRACT Engaging young learners in coding activities is increasingly important to prepare them to participate in a contemporary computationally centred society. Engagement comes from finding appropriate motivation and the use of materials and methods that are suitable to the educational stage and learning opportunities. In this article, we present our
Nicolas Gold   +3 more
wiley   +1 more source

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