Results 91 to 100 of about 452,235 (280)

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

open access: yes
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana   +8 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Digital Image Access & Retrieval [PDF]

open access: yes, 1997
The 33th Annual Clinic on Library Applications of Data Processing, held at the University of Illinois at Urbana-Champaign in March of 1996, addressed the theme of "Digital Image Access & Retrieval." The papers from this conference cover a wide range of ...
Heidorn, P. Bryan, Sandore, Beth
core  

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Investigation into Indexing XML Data Techniques [PDF]

open access: yes, 2014
The rapid development of XML technology improves the WWW, since the XML data has many advantages and has become a common technology for transferring data cross the internet.
Joan, Lu, Klaib, Alhadi
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Adaptation Rate of Structural Requirements on the Iranian Medical Journals with the Criteria of Indexing Based on Scopus

open access: yesپیاورد سلامت, 2017
Background and Aim: In the recent years the number of science research health journals has increased in Iran. These journals should be based on the standards and criteria required in international indexing database. The aim of this study was to determine
Azam Shahbodaghi   +3 more
doaj  

Are letters to the Editor Published in the Journal of Alzheimer’s Disease Undervalued? [PDF]

open access: yesNeurology Letters
Letters to the editor (LTEs) play small, but sometimes important, functions, in biomedicine, including the neurosciences. Journal of Alzheimer’s Disease (JAD), a prominent and solidly ranked (Q2 on SJR, #43) journal dedicated exclusively to this ...
Jaime A. Teixeira da Silva
doaj   +1 more source

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