Results 101 to 110 of about 452,235 (280)
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Machine aided indexing from natural language text [PDF]
The NASA Lexical Dictionary (NLD) Machine Aided Indexing (MAI) system was designed to (1) reuse the indexing of the Defense Technical Information Center (DTIC); (2) reuse the indexing of the Department of Energy (DOE); and (3) reduce the time required ...
Genuardi, Michael T. +2 more
core +1 more source
Organizing and Indexing Photo Collections [PDF]
, 2012 Historical photo archives or collections can put an organization on the map and make it into a destination for patrons. Conversely, if not well organized and indexed, collections and archives can languish in obscurity and occupy valuable space and ...
Fortier, Rose
core +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
User Motives for Tagging Video Content [PDF]
, 2008 User tagging of video content provides many possibilities for indexing and personalization. To exploit these possibilities, users must be willing to tag the video content they watch.
Melenhorst, Mark, Velsen, Lex van
core +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
The computer integrated documentation project: A merge of hypermedia and AI techniques [PDF]
To generate intelligent indexing that allows context-sensitive information retrieval, a system must be able to acquire knowledge directly through interaction with users.
Boy, Guy, Mathe, Nathalie
core +1 more source
Nonmagnetic, explosive actuated indexing device Patent [PDF]
, 1967 Development of non-magnetic indexing device for orienting magnetic flux sensing instrument in magnetic field without generation of detrimental magnetic ...
Bauernschub, J. P., Jr.
core +1 more source
NKCC1: A key regulator of glioblastoma progression
Molecular Oncology, EarlyView.Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source