Results 171 to 180 of about 1,408,736 (313)

A phase 1 evaluation of inhaled oxytocin: Physiologically‐based pharmacokinetic model informed dosing of a novel heat‐stable oxytocin delivery system

British Journal of Clinical Pharmacology, EarlyView.
Aim To develop and validate a physiologically‐based pharmacokinetic (PBPK) model enabling inhaled oxytocin dose selection for clinical evaluation. Subsequently, to conduct a phase 1 study investigating the pharmacokinetics and safety of selected doses of an optimized inhaled oxytocin product in healthy, non‐pregnant female participants.
Pete Lambert, Carl M. J. Kirkpatrick, Rory Marriott, Siladitya Ray Chaudhuri, David Polidori, Bart Remmerie, Michelle P. McIntosh   +6 more
wiley   +1 more source

A Panel Data Analysis of General Elections Under Multi Party Electoral College [PDF]

We analyze the probability of an incumbents winning in the consecutive election, under the assumption that all individual candidates are equally likely (i.e. random selection) when they are from the same party.
Jayesh Kumar
core  

HLA genotype testing for carbamazepine, oxcarbazepine and eslicarbazepine: A guideline developed by the UK Centre of Excellence in Regulatory Science and Innovation in Pharmacogenomics (CERSI‐PGx)

British Journal of Clinical Pharmacology, EarlyView.
Carbamazepine is licensed in the United Kingdom for the treatment of epilepsy, bipolar disorder and trigeminal neuralgia. The related compounds oxcarbazepine and eslicarbazepine are licensed for the treatment of epilepsy. These drugs can cause immune‐mediated hypersensitivity reactions, which typically affect the skin, and can be of variable severity ...
Lucy Galloway, Cinzia Dello Russo, Nicholas Bass, Elvira Bramon, Helen Cross, Natalie Curley, Sarah Curran, Helen Davies, Jana De Villiers, William Evans, Bernhard Frank, Alice Groves, Judith Hayward, Jon Higham, Dyfrig A. Hughes, Shwe Sin Kyaw, Anthony G. Marson, Ailsa McLellan, Seth Mensah, Francis O'Neill, Jane Sargison, Sanjay M. Sisodiya, Jill Swan, Joanna M. Zakrewska, Munir Pirmohamed   +24 more
wiley   +1 more source

Management of primary congenital glaucoma in the Indian population. [PDF]

Indian J Ophthalmol
Tripathi M, Gupta V, Gupta S.
europepmc   +1 more source

Survival outcomes and prognosis predictors of uveal melanoma from Indian population. [PDF]

Indian J Ophthalmol
Sahare H.
europepmc   +2 more sources

Patients on statins with elevated transaminases: Frequency of follow‐up creatine kinase testing and gastroenterology referral

British Journal of Clinical Pharmacology, EarlyView.
Abstract Purpose To quantify how often creatine kinase (CK) is measured after newly elevated aminotransferases in statin users, and whether absent CK data are associated with gastroenterology (GI) referrals. Methods Retrospective chart review of adult outpatients on statins with a first alanine/aspartate aminotransferase (ALT/AST) elevation during a 5 ...
Faris Shweikeh, Anas Kartoumah, Rajshri Joshi, Anjali Nadihaan, Mohammed Mouchli, Inderprit Singh   +5 more
wiley   +1 more source

Reconstructing the pharmacogenomic landscape of psychiatric medication metabolism in the Indian population. [PDF]

Commun Med (Lond)
Garg R, Saxena SK, Singh V, Kumar A, Bashir S, Singh H, Chahal N, Sharma I, Sharma V.   +8 more
europepmc   +1 more source

Making teaching an attractive profession: What are the challenges and opportunities for minority ethnic teachers in England?

British Educational Research Journal, EarlyView.
Abstract This paper explores the challenges and opportunities surrounding the recruitment and retention of minority ethnic teachers in England. Drawing on interview data from 33 teachers and school leaders of diverse ethnic backgrounds, it investigates whether racialised barriers identified in earlier research have shifted in the current context of ...
Antonina Tereshchenko, Feyisa Demie, Stephen Gorard, Yiyang Gao, Beng Huat See, Nadia Siddiqui   +5 more
wiley   +1 more source

Actionable genomic landscape of biliary tract cancer in the Indian population. [PDF]

Oncologist
Limaye S, Shreenivas A, Patil D, Vyas S, George IA, Sambath J, Singh S, Madre C, Parab A, Kataria P, Shah D, Shah N, Dawood S, Rohatgi N, Deshpande R, Datta A, Shamsi HA, Gaya A, Vaid AK, Kulkarni S, Rajappa S, Rieke D, Kumar P, Datar R, Javle M.   +24 more
europepmc   +1 more source

EXPORT POTENTIAL OF INDIA IN LIVESTOCK SECTOR: STRATEGY, PROSPECTS AND POLICY ISSUES [PDF]

Despite constraints like rearing of livestock under sub optimal conditions due to low economic status of livestock owners, India has now become the largest producer of milk in the world.
Shah, Deepak
core   +1 more source