Results 101 to 110 of about 181,723 (258)

Early Versus Late Recurrence in Olfactory Neuroblastoma: A Multi‐Institutional Analysis of Predictive Risk Factors

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Olfactory neuroblastoma (ONB) exhibits variable recurrence patterns, with significant late recurrences occurring years after treatment. We investigated cutoff periods to define late recurrence and identified predictors that distinguish patients at risk of late recurrence from those considered cured.
Alexandria Harris   +23 more
wiley   +1 more source

Glutathione‐Responsive Acyl‐Modifications for Targeted RNA Decaging and Prolonged Protein Synthesis

open access: yesAngewandte Chemie, EarlyView.
The self‐immolation of disulfide‐based mRNA modifications in response to endogenous glutathione (GSH) promotes a gradual release of translatable mRNA within the cell, leading to improved nuclease resistance, tunable release properties, and a significant increase (up to 600%) of target protein production over time. This strategy offers an exciting proof
Mary E. Flood   +6 more
wiley   +2 more sources

Development and Reliability Testing of the Sinonasal Assessment of Reepithelialization, a Novel Wound Healing Scale to Assess Postoperative Healing

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Sinus and skull base surgery create areas of demucosalized bone and cartilage in the sinonasal cavity, yet no standardized system exists to describe the progressive healing of these wounds. The goal of this study was to develop the novel Sinonasal Assessment of Reepithelialization (SNARE) and perform parametric testing including ...
Rohan Bellary   +20 more
wiley   +1 more source

Evolutionäre, funktionelle und mechanistische Charakterisierung mikrobieller Terpensynthase‐ähnlicher Gene aus Springschwänzen

open access: yesAngewandte Chemie, EarlyView.
Eine Genomanalyse zeigte das Vorkommen zahlreicher Terpensynthasen des bakteriellen Typs in Springschwänzen. Vier Enzyme aus Sinella curviseta wurden funktionell charakterisiert, was zur Isolierung mehrerer Verbindungen führte, darunter Sinellenether, der erste identifizierte Diterpenether einer Terpensynthase mit einem neuartigen Grundgerüst.
Min Wang   +5 more
wiley   +1 more source

Evolutionary, Functional and Mechanistic Characterisation of Microbial Terpene Synthase‐Like Genes From Springtails

open access: yesAngewandte Chemie International Edition, EarlyView.
A genome analysis revealed the presence of many bacterial‐type terpene synthases in springtails. Four enzymes from Sinella curviseta were functionally characterised, resulting in the isolation of several compounds including sinellene ether, the first diterpene ether identified from a terpene synthase that represents a novel skeleton.
Min Wang   +5 more
wiley   +1 more source

Racial Disparities and Personal Responsibility Incentives in Medicaid. [PDF]

open access: yesHealth Serv Res
Craig DM   +6 more
europepmc   +1 more source

Genomic characterization and comparative analysis of multidrug-resistant <i>Salmonella</i> Indiana sequence type 17 carrying <i>mcr-9.1</i> in retail eggs from the United Arab Emirates. [PDF]

open access: yesFront Vet Sci
Habib I   +9 more
europepmc   +1 more source

Dental anomalies in Pleistocene African hippopotamuses from Olduvai Bed II

open access: yesThe Anatomical Record, EarlyView.
Abstract Hippopotamuses are key palaeoenvironmental indicators in African Pleistocene ecosystems due to their ecological dependence on permanent water bodies and their frequent representation in the fossil record. This study examines dental anomalies in Hippopotamus cf. gorgops from several localities in Bed II of Olduvai Gorge (Tanzania), dated to ca.
Darío Fidalgo   +4 more
wiley   +1 more source

The 9+ month marathon: How pregnancy may have shaped human endurance capacities

open access: yesThe Anatomical Record, EarlyView.
Abstract Anthropology has long considered the evolution of our uniquely human endurance capacities to be the result of selection upon anatomical and physiological features imposed by the demands of thermoregulation and resource acquisition, particularly during the demands of persistence hunting. Research has focused on the anatomical changes present in
Cara Ocobock
wiley   +1 more source

Correction: Distinct social network structures and their cognitive and psychological correlates. [PDF]

open access: yesSci Rep
Hamilton LJ   +5 more
europepmc   +1 more source

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