Results 161 to 170 of about 181,723 (258)

Utility of Fine Needle Aspiration Supernatant for Real‐Time PCR–Based Mutation Analysis in Non–Small Cell Lung Cancer

Diagnostic Cytopathology, EarlyView.
ABSTRACT Background The emergence of personalized therapy and molecular sequencing has significantly transformed the management of advanced non–small cell lung carcinoma (NSCLC). Supernatants obtained from fine needle aspiration (FNA) have been shown to be a reliable source of high‐quality nucleic acid for molecular testing.
Adeyinka Akinsanya, Riley Gorden, Madison Rector, Hamna Muhammad, Melissa Randolph, Matt Sperling, Kemin Xu, Sheila Segura, Omer Saeed, Tieying Hou   +9 more
wiley   +1 more source

A novel antiviral strategy targeting human metapneumovirus through pH modulation in human airway epithelial cells. [PDF]

J Gen Virol
Daniels IA, Gaston B, Saunders J, Smith L, Whitlow T, Tilston NL, Relich RF, Lunel A, Davis MD.   +8 more
europepmc   +1 more source

Rapid Synthesis of Weinreb Amides via Titanium‐Mediated Direct Amidation at Room Temperature

European Journal of Organic Chemistry, EarlyView.
Rapid titanium‐mediated direct amidation enables the room‐temperature synthesis of Weinreb amides directly from carboxylic acids under mild conditions. The operationally simple protocol delivers a broad substrate scope in good to excellent yields, including challenging fluorinated substrates, without the need for conventional coupling reagents ...
Aman G. Singh, Henry J. Hamann, P. Veeraraghavan Ramachandran   +2 more
wiley   +1 more source

Prevalence of infection in amputations in patients with diabetic foot ulcer: a retrospective study. [PDF]

Front Clin Diabetes Healthc
Depinet K, Hockman B, Muraru R, Ajayi DA, Carr Z, Altenburger B, Haan J, Westin G, Holler E, Harle CA, Sinha M.   +10 more
europepmc   +1 more source

Responsive stimulation of the thalamus for idiopathic generalized epilepsy: Results of the randomized controlled NAUTILUS trial through 18 months

Epilepsia, EarlyView.
Abstract Objective This study was undertaken to evaluate the safety and effectiveness of responsive thalamic stimulation as adjunctive therapy for drug‐resistant idiopathic generalized epilepsy (IGE) with generalized tonic–clonic seizures (GTCSs). Methods NAUTILUS is a prospective, multicenter, single‐blind, randomized sham‐controlled pivotal trial ...
Utku Uysal, Patrick Landazuri, David E. Burdette, Sanjay Patra, Angela N. Crudele, Dario J Englot, Jay R. Gavvala, Sandipan Pati, Lesley C. Kaye, Steven Ojemann, Daniel Barnett, Joseph Neimat, Adriana E. Palade, Shervin Rahimpour, Amir A. Arain, Robert Mark Richardson, Sydney S. Cash, Vicenta Salanova, Alexandra Urban, William P. Welch, Jamie Joseph Van Gompel, Keith Starnes, David Spencer, Lia D. Ernst, Ushtar Amin, Angelica Rivera‐Cruz, Patricia Dugan, Marytery Fajardo, Matt Lallas, Barbara C. Jobst, Nicole Odom, Jarod L. Roland, Jon T. Willie, Sameer A. Sheth, Alica M. Goldman, Christopher T. Skidmore, Chengyuan Wu, Cornelia Drees, Jonathon Parker, Taneeta Mindy Ganguly, Jerzy Szaflarski, Saadi Ghatan, Lise Johnson, Jacob Norman, Brett Wingeier, Cairn G. Seale, Martha J. Morrell, Nautilus Study Group   +47 more
wiley   +1 more source

Region- and season-specific exposure to lead in a common North American songbird. [PDF]

Ecotoxicology
Ohrberg ML, Becker DJ, Filippelli GM, Ketterson ED, Rader ST, Reed SM, Williams EJ, Jahn AE.   +7 more
europepmc   +1 more source

Epilepsy‐associated SCN2A‐L1342P mutation drives network hyperexcitability and widespread transcriptomic changes in human cortical organoids

Epilepsia, EarlyView.
Abstract Objective SCN2A pathogenic mutations, such as the recurrent heterozygous Nav1.2‐L1342P, are monogenic causes of epilepsy. In this human‐induced pluripotent stem cell–derived model system, we aim to investigate the molecular and cellular mechanisms underlying SCN2A‐L1342P‐associated pathology. Methods Using a human male induced pluripotent stem
Maria I. Olivero‐Acosta, Morgan Robinson, Zhefu Que, Zaiyang Zhang, Karen V. Salazar‐Salazar, Hope Elizabeth Harlow, Vinayak Shankar, Seoyeon Hong, Muhan Wang, Conrad M. Otterbacher, Hina Kadono, Manasi Halurkar, Harish Kothandaraman, Nadia Atallah Lanman, Trang Nguyen, Kyle Wettschurack, Benjamin Zirkle, Layan Yunis, Ningren Cui, Xiaoling Chen, Jingliang Zhang, Jiaxiang Wu, William C. Skarnes, Chongli Yuan, Feng Guo, Megan Abbott, Yang Yang   +26 more
wiley   +1 more source

An early protective effect of IL-9 in murine systemic lupus erythematosus. [PDF]

Immunohorizons
Krishnan MS, Zhou B, Yang D, Goncalves JI, Jackson KG, Xue GR, Turner MJ, Kaplan MH.   +7 more
europepmc   +1 more source