Results 131 to 140 of about 197 (188)

Modulation of Lung Adenocarcinoma by Phosphorylated FOXN3‐Mediated Transcriptional Inactivation of p53

Advanced Science, EarlyView.
In non‐tumorous lung tissues, FOXN3 promotes the transcriptional activation of p53 by facilitating its recruitment to target promoters, thereby suppressing lung tumorigenesis through activation of the p53 signaling pathway. Conversely, in lung adenocarcinoma tissues, hyperphosphorylated FOXN3 dissociates from the promoters of p53‐responsive genes and ...
Jinjin Yu, Jingyu Yu, Suhui Wang, Xinghong Hu, Lele Jin, Nan Wu, Yuhan Ni, Xueying Zhang, Chengling Zhao, Jihong Zhou, Yong Zhang, Baofa Sun, Hongxing Zhang, Chunfu Zheng, Song Guo Zheng, Wei Li, Xinxing Zhu   +16 more
wiley   +1 more source

Anisotropic Memristive Switching in NbOCl2 Enabled by Directional Oxygen Ion Migration

Advanced Science, EarlyView.
This study investigates strongly orientation‐dependent memristive switching in anisotropic NbOCl2, observed exclusively along the in‐plane c‐axis. The switching originates from direction‐selective oxygen‐ion migration and vacancy propagation that modulate the Pd/NbOCl2 Schottky barrier, enabling short‐term plasticity.
Caokun Wang, Yun Ji, Sanchali Mitra, Yufei Shi, Haofei Zheng, Yee Sin Ang, Kah‐Wee Ang   +6 more
wiley   +1 more source

A Generative Neuro‐Symbolic AI for Protein Sequence Design

Advanced Science, EarlyView.
We introduce EffieDes, a neuro‐symbolic framework coupling deep learning‐based fitness landscape parameterization with exact automated reasoning. Unlike greedy sampling, EffieDes identifies sequences that globally optimize fitness while satisfying intricate design constraints.
Marianne Defresne, Delphine Dessaux, Samuel Buchet, Lucie Barthe, Liza Ammar‐Khodja, Bessam Azizi, Valentin Durante, Gianluca Cioci, Simon de Givry, Alain Roussel, Luis F. Garcia‐Alles, Thomas Schiex, Sophie Barbe   +12 more
wiley   +1 more source

RPLP2 Mediates the Beneficial Effects of Exercise on Stress Resistance Through Muscle–Brain Communication

Advanced Science, EarlyView.
A novel exercise‐inducible myokine acidic ribosomal protein P2 (RPLP2), initially identified from human trials, is presented here, whose circulating levels negatively correlate with clinical anxiety severity. Muscle‐derived RPLP2 enhances hippocampal ribosomal assembly and adult neurogenesis to rescue stress‐induced anxiety deficits.
Peiyu Luo, Wei Wu, Huan Peng, Dan He, Yuxi Guo, Boyue Zhao, Xiaodan Wang, Li Ma, Yuhang Qin, Yifang Zhai, Lixia Zhuo, Ying Zhang, Yijie Guo, Linlin Jing, Fangyao Chen, Erfei Zhang, Wei Wang, Xiancang Ma, Yan Li   +18 more
wiley   +1 more source

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Indicative conditionals

Philosophia (United States), 1975
AbstractAims to reconcile a unified semantic account of conditional statements with an apparent contrast between the logics of indicative and ”subjunctive” conditionals. The difference between the two kinds of conditionals is explained in terms of different constraints imposed on the contexts relative to which the different forms of conditionals are ...
Robert Stalnaker
exaly   +2 more sources

Indicative conditionals:Factual or Epistemic?

Studia Logica, 2008
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
John Cantwell, Cantwell John
exaly   +3 more sources

Indicative conditionals

2018
This chapter defends a probabilistic semantics for indicative conditionals and other logical operators. This semantics is motivated in part by the observation that indicative conditionals are context sensitive, and that there are contexts in which the probability of a conditional does not match the conditional probability of its consequent given its ...
exaly   +2 more sources

The Subjectivity of Indicative Conditionals

2003
AbstractDiscussion of reasons for approaching indicative conditionals in terms of subjective rather than objective probability. The reasons include stand‐offs of the sort Gibbard has presented: cases where two right‐thinking people with partial information accept conflicting conditionals.
Bennett Jonathan
exaly   +2 more sources

Uses of Indicative Conditionals

2003
AbstractDiscussion of the uses of indicative conditionals. Reasons for holding that when the antecedent is true, the conditional has the same truth value as the consequent. Conditionals as ‘inference‐tickets’. Non‐interference conditionals: ‘Even if A, still C’. So‐called ‘biscuit conditionals’.
Bennett Jonathan
exaly   +2 more sources

Indicative Conditionals in Awareness Framework

Lecture Notes in Computer Science, 2023
exaly   +2 more sources