We establish a tBid‐mediated cell ablation system in axolotls, achieve rapid and efficient ablation of multiple cell types, including muscle stem cell, spinal cord cell, and connective tissue (CT) cells. We investigate the role of CT using tBid‐mediated CT ablation and identify its essential role for limb development and regeneration.
Yan Hu +11 more
wiley +1 more source
Comment on: Probabilities of conditionals: The relevance effect might be confounded by the existence of boundary cases (2025) by Zhan and Wang. [PDF]
Skovgaard-Olsen N, Klauer KC.
europepmc +1 more source
Engaging the public: English local government organisations' social media communications during the COVID-19 pandemic. [PDF]
Love R, Darics E, Palmieri R.
europepmc +1 more source
Engineering Microbial Particles for Next‐Generation Biomedical Platforms
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li +7 more
wiley +1 more source
Causal Conditionals, Tendency Causal Claims and Statistical Relevance. [PDF]
Sikorski M, van Dongen N, Sprenger J.
europepmc +1 more source
Tomato Cultivars With Variable Tolerances to Water Deficit Differentially Modulate the Composition and Interaction Patterns of Their Rhizosphere Microbial Communities. [PDF]
Gaete A +9 more
europepmc +1 more source
Achieving High‐Density and Stress‐Resilient Maize Breeding Via Germplasm Innovation
Global population growth and climate change have exacerbated the global food crisis. This perspective presents a conceptual framework focusing on enhancing population advantages. Several novel breeding objectives are proposed to improve density tolerance and stress resistance for yield improvement.
Xinlong Li +9 more
wiley +1 more source
Reasoning about possibilities: Modal logics, possible worlds, and mental models. [PDF]
Johnson-Laird PN, Ragni M.
europepmc +1 more source
Dysregulated TCA cycle contributes to Alzheimer's disease (AD) pathogenesis. Here, we show that microglial isocitrate dehydrogenase 1 (IDH1) is a critical driver. Elevated IDH1 disrupts citrate metabolism and mitochondrial function, exacerbating AD pathology.
Qianqian Li +13 more
wiley +1 more source
A Partial Modal Semantics for the Adams Logic of Indicative Conditionals
Adams p-entailment provides a probabilistic extension of sentential logical consequence to simple indicative conditionals. Adams approach, taken together with David Lewis’ Triviality Results, supports the view that indicative conditionals of the form p ⇒
MURA, Alberto Mario
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