Results 71 to 80 of about 369,778 (264)

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Breeding habitat selection of Canada Warblers across three distinct landscapes in Québec

open access: yesAvian Conservation and Ecology
We investigated the breeding habitat selection of the Canada Warbler ( Cardellina canadensis ) in southern Quebec across three distinct landscapes: a mixed boreal forest, an agroforestry landscape, and a riverine deciduous forest.
Samuel Dufour-Pelletier   +5 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Floristic Diversity, Indicator and Suitable Species for Andean Livestock in the Sillapata Micro-Watershed, Acopalca

open access: yesInternational Journal of Plant Biology
Andean grassland ecosystems in Peru are characterized by diverse plant species adapted to environmental factors including weather, soil type, elevation, slope orientation, and soil moisture. This study evaluated the floristic composition, alpha diversity,
Raúl M. Yaranga   +3 more
doaj   +1 more source

Does riparian vegetation affect fish assemblage? A longitudinal gradient analysis in three Amazonian streams

open access: yesActa Scientiarum: Biological Sciences, 2018
  The degradation of riparian vegetation in low-order streams can cause irreversible environmental damage, biodiversity loss and alter the structure of communities.
Lucena Rocha Virgilio   +5 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Diversidad de hormigas (Hymenoptera: Formicidae) en un gradiente sucesional del bosque nublado (Nariño, Colombia)

open access: yesRevista de Biología Tropical, 1999
Para evaluar el uso de las hormigas como indicadores ecológicos del grado de recuperación del bosque en la Reserva Natural La Planada (Nariño, Colombia), se colectaron hormigas entre Febrero y Agosto de 1995 en siete lugares correspondientes a un ...
Catalina Estrada M   +1 more
doaj  

Monitoring the Growth and Habitat Shifts of Epiphyllous Liverworts in Subtropical Forests of China

open access: yesEcology and Evolution
Understanding the extent to which species can adjust their ranges in response to climate change and track areas of suitable climatic conditions is vital for conservation efforts.
Zun Dai   +7 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

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