Results 131 to 140 of about 152,483 (320)

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Designing a Questionnaire for Prenatal Health Care

open access: yesArmaghane Danesh Bimonthly Journal, 2019
Background & aim: The purpose of this study was to design a questionnaire for prenatal health care in order to step through the design of a standard tool for measuring and promoting prenatal care.
I Na'imi   +2 more
doaj  

Tracer sensitive tapes [PDF]

open access: yes
A leak detection system has been developed, consisting of a tape that can be wrapped around possible leak sites on a system pressurized with air or gaseous nitrogen.
Burrows, W. H., Burrows, W. H.
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Efficient recovery of phosphorus from phosphogypsum leachate based on struvite precipitation

open access: yes能源环境保护
Phosphogypsum leachate is a liquid produced during phosphogypsum stacking. It has the characteristics of high phosphorus content, low pH, high corrosivity, and high concentrations of heavy metals.
MA Jingfeng   +5 more
doaj   +1 more source

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