Results 111 to 120 of about 84,912 (298)

Indicators of Moderate and Severe Preeclampsia in Correlation with Maternal IL10

, 2016
AIM: The purpose of the actual study was to evaluate the relationship between the formation of anti-inflammatory cytokine IL10 and several indicators of moderate and severe preeclampsia in the third trimester of pregnancy.MATERIAL AND METHODS ...
Hadži-Lega, Marija, Daneva Markova, Ana, Mijakoski, Dragan   +2 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Development of sustainable water treatment technology using scientifically based calculated indexes of source water quality indicators

, 2017
The article describes selection process of sustainable technological process flow chart for water treatment procedure developed on scientifically based calculated indexes of quality indicators for water supplied to water treatment facilities.
A. S. Tryakina
core   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

[The quality indices of the Quick method using thromboplastin reagents performed manually and instrumentally].

Klinicheskaia laboratornaia diagnostika, 2000
The reproduction and results of Quick's method with tissue thromboplastin (Kirov Institute of Hematology and Blood Transfusion--KIHBT) and Excel and Excel S simplastins (Organon Teknika, Netherlands) in the tube and automated versions were compared.
L N, Tarasova, S G, Vladimirova, E Iu, Savinykh, G K, Platonov, O I, Rechkin   +4 more
openaire   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Porphyrin-modified antimicrobial peptide indicators for detection of bacteria

, 2016
This study demonstrates the potential of porphyrin modified antimicrobial peptides for indication of bacterial targets on the basis of changes in the spectrophotometric characteristics of the construct.
Apre Gleaves, Johnson, Brandy J., Chris R. Taitt, Gleaves, Apre, Brandy J. Johnson, Malanoski, Anthony P., Edikan Archibong, North, Stella H., Leska, Iwona A., Monk, Stormie M., Anthony P. Malanoski, Archibong, Edikan, Iwona A. Leska, Stormie M. Monk, Taitt, Chris R., Stella H. North   +15 more
core   +1 more source

Designing a Questionnaire for Prenatal Health Care

Armaghane Danesh Bimonthly Journal, 2019
Background & aim: The purpose of this study was to design a questionnaire for prenatal health care in order to step through the design of a standard tool for measuring and promoting prenatal care.
I Na'imi, P Aghaei Borzabad, A Yazdanpanah   +2 more
doaj  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source