Results 81 to 90 of about 153,076 (312)

Origin and fluxes of atmospheric REE entering an ombrotrophic peat bog in Black Forest (SW Germany): Evidence from snow, lichens and mosses [PDF]

open access: yes, 2006
The fate of the Rare Earth Elements (REE) were investigated in different types of archives of atmospheric deposition in the Black Forest, Southern Germany: (1) a 70 cm snow pack collected on the domed part of a raised bog and representing 2 months of ...
Aubert, Dominique   +6 more
core   +3 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

Application of quality monitoring indicators of blood testing in blood banks of Shandong province

open access: yesZhongguo shuxue zazhi
Objective To objectively evaluate the quality control level of blood testing process in blood banks through quantitative monitoring and trend analysis, and to promote the homogenization level and standardized management of blood testing laboratories in ...
Xuemei LI   +26 more
doaj   +1 more source

[The quality indices of the Quick method using thromboplastin reagents performed manually and instrumentally].

open access: yesKlinicheskaia laboratornaia diagnostika, 2000
The reproduction and results of Quick's method with tissue thromboplastin (Kirov Institute of Hematology and Blood Transfusion--KIHBT) and Excel and Excel S simplastins (Organon Teknika, Netherlands) in the tube and automated versions were compared.
L N, Tarasova   +4 more
openaire   +1 more source

Review of Universal Salt Iodation in East Central and Southern Africa (ACSA) [PDF]

open access: yes, 1997
\ud This paper presents a regional position on Universal Salt Iodation (USI) intervention in 14 countries ill the East, Central and Southern Africa( ECSA) region,namely;Botswana,Kenya,Malawi,Mauritius,Mozambique,Namibia,bells,South Africa, Swaziland ...
Commonwealth Regional Hearth Community Secretariat for East Central and Southern Africa, CRHCS/ECSA
core  

Real-time sweat pH monitoring based on a wearable chemical barcode micro-fluidic platform incorporating ionic liquids [PDF]

open access: yes, 2012
This work presents the fabrication, characterisation and the performance of a wearable, robust, flexible and disposable chemical barcode device based on a micro-fluidic platform that incorporates ionic liquid polymer gels (ionogels).
Beauchamp   +41 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Development Of Ecologically Safe Technology Of Waste Mycelia Recycling [PDF]

open access: yes, 2017
Chitosan is a cationic polymer derived by deacetylation of chitin obtained from crustaceans. Biodegradable and mucoadhesion properties of chitosan have recently led to increasing the interest.
Yegorova, O. (Oksana)
core   +2 more sources

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