Results 31 to 40 of about 88,428 (214)
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Direct and Indirect Effects [PDF]
, 2022 The direct effect of one eventon another can be defined and measured byholding constant all intermediate variables between the two.Indirect effects present conceptual andpractical difficulties (in nonlinear models), because they cannot be isolated by holding certain variablesconstant. This paper shows a way of defining any path-specific effectthat does
openaire +4 more sources
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Acta Economica, 2012 The key issue being of interest to all investors, both big and small ones, is how to make a realistic assessment of the value of some company’s shares and which parameters should be taken into account when making a decision whether to sell or buy certain
Миро Џакула
doaj
Implications of the taxation of tobacco in the European Union in the period 2005-2014
Financial Theory and Practice, 2015 The paper aims to analyze the implications of excise policy in member states and at the EU level in the period 2005-2014 in the field of tobacco taxation for policy convergence, revenues and the tobacco market.
Dinka Antić
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
APPLICATION OF 3D DIGITAL SCANNING AND CAD/CAM SYSTEMS FOR ZIRCONIA INDIRECT RESTORATIONS [PDF]
Journal of IMAB, 2016 Object: To study the CAD/CAM systems’ possibilities for manufacturing Zirconia indirect restorations for restoring vital, vastly devastated teeth. Material and methods: Five patients with vital, heavily destroyed molars were included in the clinical ...
Mariela Tsanova +2 more
doaj +1 more source
Comparison of Clinical Characteristics and Predictors of Mortality between Direct and Indirect ARDS
Medicina, 2022 Background and Objectives: Acute Respiratory Distress Syndrome (ARDS) is a heterogeneous syndrome that encompasses lung injury from a direct pulmonary or indirect systemic insult.
Wen Tang +4 more
doaj +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source