Results 51 to 60 of about 88,428 (214)
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
A Survey of Indirect Reciprocity [PDF]
, 2007 This survey deals with indirect reciprocity, i.e. with the possibility that altruistic acts are returned, not by the recipient, but by a third party. After briefly sketching how this question is dealt with in classical game theory, we turn to models from evolutionary game theory.
Brandt, H. +3 more
openaire +4 more sources
RNA‐related functions of BRCA2 in transcription, replication, and genome stability
FEBS Letters, EarlyView.Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda +2 more
wiley +1 more source
Economic Review, 2011 This paper is focused on the process of evaluating performance of employees. Special emphasis has been put on possible errors that may impair the objectivity of the outcome of this process.
Adisa Delić, Mirela Ćebić
doaj
Condition Monitoring of Railway Bridges Using Vehicle Pitch to Detect Scour
SensorsThis study proposes the new condition monitoring concept of using features in the measured rotation, or ‘pitch’ signal, of a crossing vehicle as an indicator of the presence of foundation scour in a bridge. The concept is explored through two-dimensional
Claire McGeown +5 more
doaj +1 more source
CLOSED-LOOP SUPPLY CHAIN WITH DELIVERY LEAD TIME ON DIRECT AND INDIRECT CHANNEL
Barekeng, 2020 The responsbility of protecting the environment rest with all parties, including manufacturers. Therefore, manufacturers reprocess their used products. Mathematically, it can be explained by closed-loop supply chain (CLSC) model. CLSC is a system that is
Endang Sulastri +2 more
doaj +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
REFLECTIONS OF THE EU EXCISES POLICY ON DYNAMICS OF ASSOCIATION OF BIH IN LIGHT OF GLOBAL CHALLENGES
Acta Economica, 2009 Dedication of Bosnia and Herzegovina to European integrations requires a fulfilment of pre-accession obligations that relate to harmonization on excises taxation in BiH with the EU standards.
Динка Антић, PhD
doaj
Acta Ortopédica Brasileira, 2002 A avulsão da cartilagem da crista ilíaca é uma lesão infreqüente e raramente é descrita na literatura. Atletas jovens e adolescentes são os indivíduos mais predispostos à lesão.
Gilberto José Cação Pereira +2 more
doaj +1 more source