Results 41 to 50 of about 7,123,707 (163)
Fucosylation limits ADCC in clinically used anti‐RhD monoclonal antibodies
Abstract Background Haemolytic disease of the fetus and newborn (HDFN) is caused by maternal alloantibodies, often targeting the D antigen on fetal red blood cells. Maternal immunization is preventable with timely administration of anti‐D polyclonal antibodies (pAbs).
Gabriela Koike +33 more
wiley +1 more source
ALECTINIB-RELATED ERYTHROCYTE MEMBRANE CHANGES, NON-IMMUNE HEMOLYSIS AND ERYPTOSIS
Objective: Alectinib is an anaplastic lymphoma kinase (ALK) inhibitor which standard initial treatment for patients with advanced ALK rearranged non-small-cell lung cancer (NSCLC).
Emine Gulturk
doaj +1 more source
A global survey of blood transfusion practices for patients with sickle cell disease
Abstract Background Sickle cell disease (SCD) affects over 7 million people globally, with blood transfusion remaining a cornerstone of management. However, contemporary transfusion practices across diverse settings remain poorly characterized. We evaluated global transfusion practices for patients with SCD to identify gaps and inform resource ...
Jeremy W. Jacobs +18 more
wiley +1 more source
This is a sample submission generated by Vireo to test the repository deposit features.Test ...
Submitter, Test
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Abstract Background CD47‐targeted agents can interfere with pretransfusion testing due to CD47 expression on red blood cells (RBCs). IMC‐002 is a novel anti‐CD47 human IgG4 monoclonal antibody engineered to minimize RBC binding; however, its interference profile during pretransfusion testing remains poorly characterized.
Tae‐Shin Kim +5 more
wiley +1 more source
Clinically significant anti-Wra antibody: A report of two successfully managed patients [PDF]
Introduction. Wra is an antigen of the Diego blood group system. Anti-Wra antibody can be found in the sera of healthy individuals (naturally occurring anti-Wra) or can be immunostimulated after transfusion or after exposure to foreign erythrocytes ...
Bujandrić Nevenka +3 more
doaj +1 more source
Abstract Background Human monoclonal (MoAb) anti‐CD38 antibodies, such as daratumumab, are used to treat diseases such as multiple myeloma. Because red blood cells (RBCs) express CD38, these MoAbs interfere with antibody screening and crossmatching in blood banks.
Ayda Javanbakht +3 more
wiley +1 more source
Stability of test cells used for indirect antiglobulin technique
Background: The test cells used for indirect antiglobulin technique are diluted with Phosphate Buffered Saline (PBS) in a test tube. Test cells in PBS keep for 24 hours.
Liv Jorunn Garvik
doaj
Abstract Background and Objectives Availability of new technologies has accelerated the pace of blood group discovery, with nine of 48 known systems being discovered in the past 5 years alone, and yet uncharacterized antigens remain. This study involved investigations of samples from a female patient presenting with a moderate strength pan‐reactive ...
Tosti J. Mankelow +7 more
wiley +1 more source
ABSTRACT Common variable immunodeficiency (CVID) may initially manifest as undifferentiated connective tissue disease (UCTD) in the absence of recurrent infections or hypogammaglobulinemia. In patients presenting with warning signs, neither older age nor normal immunoglobulin levels should preclude consideration of CVID; early genetic testing is ...
Yu‐Jie Hu +4 more
wiley +1 more source

