Results 151 to 160 of about 968,367 (316)
ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
[18F]Fluorodeprenyl‐D2 PET as a Tool to Monitor Disease Activity in GAD65‐Ab Autoimmune Encephalitis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To evaluate [18F]fluorodeprenyl‐D2 ([18F]F‐DED) positron‐emission tomography (PET) imaging as a biomarker of disease activity in autoimmune encephalitis (AIE) associated with glutamic acid decarboxylase 65 (GAD65) antibodies. Methods [18F]F‐DED PET was performed in 25 GAD65‐AIE patients and 8 controls using dynamic (0–60 min) and ...
Julia S. Dorneich +19 more
wiley +1 more source
CONSTRAINED EMM AND INDIRECT INFERENCE ESTIMATION [PDF]
We develop generalised indirect inference procedures that handle equality and inequality constraints on the auxiliary model parameters. We obtain expressions for the optimal weighting matrices, and discuss as examples an MA(1) estimated as AR(1), an AR(1)
Gabriele Fiorentini +2 more
core
Decomposing heritability and genetic covariance by direct and indirect effect paths. [PDF]
PLoS Genet, 2023 Song J +6 more
europepmc +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective High‐resolution MRI enables detailed assessment of intracranial vessel wall pathology in moyamoya vasculopathy. We aimed to classify adult moyamoya vasculopathy etiologies using high‐resolution MRI and to examine subtype‐specific associations between high‐resolution MRI features and ischemic infarction.
Guangsong Han +8 more
wiley +1 more source
The Effect of Direct and Indirect Corrective Feedback on Students’ Spelling Errors
, 2011 The study presented here is an attempt to examine the role of indirect feedback in promoting junior high school students' spelling accuracy in English. It compares the effect of direct feedback with indirect feedback on students' written work dictated by
Mehdi Dadashi +3 more
core
The First Aerosol Indirect Effect: Beyond Twomey [PDF]
, 2008 The traditional first aerosol indirect effect or the Twomey effect involves several fundamental assumptions. Some of the assumptions (e.g., constant liquid water content) are explicitly stated in studies of the Twomey effect whereas others are only ...
Daum, P., Dunn, M., Liu, Y.
core
Geo-environmental factors' influence on mining operation: an indirect effect of managerial factors. [PDF]
Environ Dev Sustain, 2023 Mishra PC, Panigrahi RR, Shrivastava AK.
europepmc +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan +5 more
wiley +1 more source
A general model-based causal inference method overcomes the curse of synchrony and indirect effect. [PDF]
Nat Commun, 2023 Park SH, Ha S, Kim JK.
europepmc +1 more source