Results 51 to 60 of about 10,481,084 (312)
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Economic Efficiency Estimation for Spatially Distributed Ferrous Metallurgy Projects [PDF]
Пространственная экономикаThis study develops a modern economic analysis methodology for a comprehensive evaluation of investment projects within the ferrous metallurgy sector.
Tatiana Sergeevna Novikova +2 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Remote Sensing, 2022 Urbanization has changed the environmental conditions of vegetation growth, such as the heat island effect, which has an indirect impact on vegetation growth. However, the extent to which the direct and indirect effects of the thermal environment changes
Zhitao Feng, Zhenhuan Liu, Yi Zhou
doaj +1 more source
On the Indirect Effect of Biofuel
American Journal of Agricultural Economics, 2013 American Journal of Agricultural Economics Advance Access published June 24, 2013 O N THE I NDIRECT E FFECT OF B IOFUEL D AVID Z ILBERMAN , G EOFF B ARROWS , G AL H OCHMAN , AND D EEPAK R AJAGOPAL David Zilberman (zilber11@berkeley.edu) is a Professor and Robinson Chair in the Agricultural and Resource Economics Department at UC Berkeley and a member ...
Zilberman, David +3 more
openaire +4 more sources
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Recently, the separable indirect effect (SIE) has gained attention due to its identifiability without requiring the untestable cross-world assumption necessary for the natural indirect effect (NIE). This article systematically compares the causal assumptions underlying the SIE, NIE, and interventional indirect effect (IIE) and evaluates their ...
Chen, Yan-Lin, Lin, Sheng-Hsuan
openaire +2 more sources
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Keystone Predation: What Is It, and Is It Supported by Empirical Evidence?
Ecology and EvolutionKeystone predation is the process whereby a predator indirectly facilitates weak competitors by preferentially consuming strong competitors, often affecting local diversity.
Anthony J. Gillis +2 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source