Results 61 to 70 of about 222,357 (305)

Poly(lactic‐co‐glycolic acid) Nanoparticles for IL‐12 Self‐Amplifying RNA Delivery in Glioblastoma Models

Advanced Functional Materials, EarlyView.
xxxx. ABSTRACT Glioblastoma (GBM) remains one of the most lethal brain cancers, with median survival rarely exceeding 15 months after diagnosis. Interleukin‐12 (IL‐12) is a potent immunostimulatory cytokine capable of reshaping the tumor microenvironment (TME), yet its clinical translation is hindered by systemic toxicity and short half‐life. RNA‐based
Fatima Hameedat, Johan Sebastian Lopez‐Parra, Willem M. H. Hoogaars, Emma Dijkstra, Cynthia Huang, Irafasha C. Casmil, Anna K. Blakney, Peter Olinga, Barbara Rothen‐Rutishauser, Hélder A. Santos, Alke Petri‐Fink, Flávia Sousa   +11 more
wiley   +1 more source

Orchid viruses of natural Ukrainian flora

Plant Protection Science, 2002
Virus infection greatly affects to the normal growth and reproductive intensity of orchid species in greenhouses. Peculiarities of ornamental orchid viruses has become known in different countries of the world while there is nothing known about orchid ...
A.V. Koroteyeva, V.P. Polischuk
doaj   +1 more source

Simvastatin Restores Uteroplacental Hemodynamics and Trophoblast Function in Obstetric Antiphospholipid Syndrome in a Placenta‐on‐a‐Chip Model

Advanced Healthcare Materials, EarlyView.
Simvastatin mitigates placental hypoperfusion in OAPS by ameliorating abnormal uteromaternal hemodynamics and enhancing trophoblast invasion via optimized endothelial cell interactions under pathological shear stress, as evidenced by results from a placenta‐on‐a‐chip platform.
Hongli Liu, Yuan Wang, Yanjun Cai, Ruixin Guo, Shunhua Liu, Tingting Chen, Tingting Sun, Ruiheng Huo, Tengwei Liu, Qingfeng Lv, Xietong Wang   +10 more
wiley   +1 more source

Development of an indirect enzyme-linked immunosorbent assay for the detection of osmotolerant yeast Zygosaccharomyces rouxii in different food

Food and Agricultural Immunology, 2018
A polyclonal antibody-based indirect ELISA for the sensitive and specific detection of osmotolerant Zygosaccharomyces rouxii was established. The reactivity of the polyclonal antibodies (pAbs) with Z. rouxii was confirmed by immunofluorescence. The ELISA
Hong Guo, Ya-Hong Yuan, Chen Niu, Yue Qiu, JianPing Wei, Tian-Li Yue   +5 more
doaj   +1 more source

Evaluation and Diagnostic Potential of Serum Ghrelin in Feline Hypersomatotropism and Diabetes Mellitus [PDF]

, 2015
BACKGROUND: Ghrelin is a growth hormone secretagogue. It is a potent regulator of energy homeostasis. Ghrelin concentration is down‐regulated in humans with hypersomatotropism (HS) and increases after successful treatment. Additionally, ghrelin secretion
Appleton, Barkan, Bedendi, Belsito, Berg, Bhatti, Brearley, Briatore, Cappiello, Cummings, Dezaki, Dunning, Erdmann, Feldman, Freda, Gelling, Ida, Jenkins, Jensen, Kawamata, Kojima, Kojima, Kozakowski, Krzyzanowska-Świniarska, Martin, McLaughlin, Meij, Natalucci, Niessen, Niessen, Niessen, Niessen, Peino, Pöykkö, Reusch, Roemmler, Saad, Sofer, Soriano-Guillén, Takaya, Tschuor, Ueno, Yada   +42 more
core   +2 more sources

siRNA Delivery via Cross‐Linked Gelatin Microparticles Enables Targeted Modulation of Osteogenic‐Vascular Cross‐Talk: An Advanced Human 3D in Vitro Test System for Therapeutic siRNA

Advanced Healthcare Materials, EarlyView.
Osteogenic‐angiogenic cross‐talk is a vital prerequisite for vascularized bone regeneration. In this study, we investigated the effects of siRNA‐mediated silencing of two inhibitory proteins, Chordin and WWP‐1, via CaP‐NP‐loaded gelatin microparticles in osteogenically differentiated microtissues.
Franziska Mitrach, Jonas Kubat, Stefan Simm, Alexandra H. Springwald, Burak Demir, Anton Liebezeit, Michael C. Hacker, Michaela Schulz‐Siegmund   +7 more
wiley   +1 more source

Seroprevalence and Associated Risk Factors of Mycoplasma gallisepticum Infection in Poultry Farms of Hawasa and Bishoftu, Central Ethiopia

Veterinary Medicine: Research and Reports, 2022
Jirata Shiferaw,1 Firaol Shifara,2 Misgana Tefera,1 Abdi Feyisa,3 Yobsan Tamiru4 1Department of Pathology and Parasitology, Addis Ababa University College of Veterinary Medicine and Agriculture, Bishoftu, Ethiopia; 2College of Natural and Computational ...
Shiferaw J, Shifara F, Tefera M, Feyisa A, Tamiru Y   +4 more
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Effect of high and low levels of maternally derived antibodies on porcine circovirus type 2 (PCV2) infection dynamics and production parameters in PCV2 vaccinated pigs under field conditions [PDF]

, 2016
The present study aimed to compare the efficacy of a porcine circovirus type 2 (PCV2) commercial vaccine in terms of average daily weight gain (ADWG) as well as infection dynamics in pigs with different maternally derived antibody (MDA) levels.
Feng, H., Fraile Sauce, Lorenzo José, López-Soria, Sergio, Segalés, Joaquim, Sibila, Marina   +4 more
core   +2 more sources

Medical Fabrics with Non‐Antibiotic, Supramolecular Antimicrobial Coatings: A Preventive Approach to Combat Biofilm Formation and Bacterial Dissemination

Advanced Healthcare Materials, EarlyView.
The study presents an antibiotic‐free strategy using medical fabrics coated with supramolecular assemblies of polyarginine and hyaluronic acid. These coatings showed strong antimicrobial and anti‐biofilm activity in vitro and in vivo, achieving major bacterial load reductions, including against MRSA.
Adjara Diarrassouba, Abdessalem Rekiki, Cécile Loubière, Sabine Kuchler‐Bopp, Lauriane Petit, Cynthia Calligaro, Derry Mercer, Aurore Gaudin, Naomi Canourgues, Emilie Adicéam, Benoit Beitz, Jeremy Welsch, Annabelle Vigué, Markus j. Kettel, Michael Karl, Chloé Guilbaud‐Chéreau, Philippe Lavalle, Nihal Engin Vrana, Skander Hathroubi   +18 more
wiley   +1 more source

Serological Investigation of Newcastle Disease in Selected Districts of Buno Bedelle Zone, Ethiopia

Veterinary Medicine: Research and Reports, 2021
Tamirat Mamo,1 Lama Yimer2 1Seyo District Livestock Development Office, Dembi Dollo, Ethiopia; 2School of Veterinary Medicine, Wollega University, Nekemte, EthiopiaCorrespondence: Lama YimerSchool of Veterinary Medicine, Wollega University, Nekemte ...
Mamo T, Yimer L
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