Results 61 to 70 of about 46,824 (301)

Coagulative Granular Hydrogels with an Enzyme Catalyzed Fibrin Network for Endogenous Tissue Regeneration

open access: yesAdvanced Healthcare Materials, EarlyView.
Coagulative granular hydrogels are composed of packed thrombin‐functionalized microgels that catalyze the conversion of fibrinogen into a secondary fibrin network, filling the interstitial voids. This bio‐inspired approach stabilizes the biomaterial to match the robustness of bulk hydrogels without compromising injectability, mimicking the initial ...
Zhipeng Deng   +16 more
wiley   +1 more source

Modelling of Friction Stir Extrusion using Artificial Neural Network (ANN) [PDF]

open access: yesInternational Journal of Advanced Design and Manufacturing Technology, 2018
In the present study, an artificial neural network (ANN) model is developed to predict the correlation between the friction stir extrusion (FSE) parameters and the recycled wires’ average grain sizes.
Mohammad Ali Ansari   +3 more
doaj  

Faster - Better Molds Through RSP Tooling New Research and Advancements [PDF]

open access: yes, 2004
The recent developments in rapid production tooling have all but made the need for prototype tooling disappear. There are several approaches that are now as fast and inexpensive as prototype tooling, and after part approval can continue to run in high ...
Knirsch, James R.
core   +1 more source

Chamber‐Specific Decellularized Extracellular Matrices Differentially Modulate Cardiomyocyte Subtypes to Drive Engineered Heart Tissue Development and Function

open access: yesAdvanced Healthcare Materials, EarlyView.
Chamber‐specific decellularized extracellular matrices (ECMs) were developed, preserving native proteomic profiles of ventricular and atrial myocardium. These innate biochemical cues differentially modulate cardiomyocyte subtypes to drive engineered heart tissue development and function, highlighting the importance of incorporating regional ECM cues in
Dong Gyu Hwang   +7 more
wiley   +1 more source

Evaluation of a Conformationally Constrained Indole Carboxamide as a Potential Efflux Pump Inhibitor in Pseudomonas aeruginosa

open access: yesAntibiotics, 2022
Efflux pumps in Gram-negative bacteria such as Pseudomonas aeruginosa provide intrinsic antimicrobial resistance by facilitating the extrusion of a wide range of antimicrobials.
Yongzheng Zhang   +7 more
doaj   +1 more source

Recent advances in 3D printing of biomaterials. [PDF]

open access: yes, 2015
3D Printing promises to produce complex biomedical devices according to computer design using patient-specific anatomical data. Since its initial use as pre-surgical visualization models and tooling molds, 3D Printing has slowly evolved to create one-of ...
Chia, Helena N, Wu, Benjamin M
core   +2 more sources

Dual‐Peptide Nanoplatform: Mesoporous Silica Nanoparticles Functionalized With a Cell‐Penetrating Peptide and Loaded With Rationally Designed Antimicrobial Peptides for Tuberculosis Therapy

open access: yesAdvanced Healthcare Materials, EarlyView.
Machine learning–guided engineering of a plectasin‐derived peptide yields DC05, a potent antimycobacterial candidate. Encapsulation into tuftsin‐functionalized mesoporous silica nanoparticles enhances intracellular delivery, stability, and activity against Mycobacterium tuberculosis while maintaining low cytotoxicity and minimal hemolysis. The combined
Christian S. Carnero Canales   +12 more
wiley   +1 more source

Medial Meniscus Posterior Root Repair Using a Transtibial Technique

open access: yesArthroscopy Techniques, 2017
The meniscal roots are critical in maintaining the normal shock absorbing function of the meniscus. If a meniscal root tear is left untreated, meniscal extrusion can occur rendering the meniscus nonfunctional resulting in degenerative arthritis. Two main
Jarret M. Woodmass, M.D., F.R.C.S.C.   +3 more
doaj   +1 more source

Distinguishing damages from two earthquakes —Archaeoseismology of a Crusader castle (Al-Marqab citadel, Syria) [PDF]

open access: yes, 2010
Damages from two major earthquakes are identified in medieval Al-Marqab citadel (Latin: Margat) in coastal Syria. Built by the Order of St. John (Hospitallers) in the twelfth–thirteenth centuries, the hilltop fortification has masonry walls made with and
Kázmér, Miklós, Major, Balázs
core   +1 more source

Small Extracellular Vesicles from Neural Cells: Physiological and Pathological Roles, and Potential in Neurodegenerative Therapy

open access: yesAdvanced Healthcare Materials, EarlyView.
Neural cell–derived small extracellular vesicles (sEVs) are emerging as pivotal mediators in neurodegenerative diseases, exerting both pathogenic and therapeutic functions. This review synthesizes current evidence on how sEVs from distinct neural cell types regulate neurodegeneration, neuroprotection, biomarker discovery, and targeted drug delivery ...
Muhammad Waqas Salim   +4 more
wiley   +1 more source

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