Hillclimb-Causal Inference: a data-driven approach to identify causal pathways among parental behaviors, genetic risk, and externalizing behaviors in children. [PDF]
J Am Med Inform AssocWei M, Peng Q.
europepmc +1 more source
Electrical Control of the Transduction Channels’ Gating Force in Mechanosensory Hair Cells
Advanced Science, EarlyView.The inner ear's hair cells rely on mechanosensitive ion channels to convert vibrations of their hair‐bundle into electrical signals. We show that varying the electrical potential (U) across the sensory epithelium modulates a key determinant of mechanosensitivity—the gating force (FG)—by modulating the gating swing (d), ranging from the size of the ...
Achille Joliot +2 more
wiley +1 more source
Unveiling Global Diversity of Patescibacteriota and Functional Interactions with Host Microbes
Advanced Science, EarlyView.Patescibacteriota represents a diverse group of ultra‐small epibiotic bacteria, which is largely overlooked. By integrating ribosomal protein S3‐based community profiling with MAG‐based metabolic potential analyses, this study provides new insights into their distribution, diversity, and potential interactions with other bacteria across diverse ...
Yanhan Ji +12 more
wiley +1 more source
Uncovering heterogeneous intercommunity disease transmission from neutral allele frequency time series. [PDF]
Proc Natl Acad Sci U S AOkada T +3 more
europepmc +1 more source
A Review on Biodegradable Materials of Sustainable Soft Robotics and Electronics
Advanced Science, EarlyView.Biodegradable materials are gaining increasing attention in soft robotics and electronics due to their environmental friendliness, showing great potential for sustainability. In this review, the classification of biodegradable materials, their applications in the field of soft robotics and electronics, as well as the challenges and future prospects ...
Yizhu Xie +8 more
wiley +1 more source
Associations between the living environment and sleep through the mediation of the physical activity: a systematic review. [PDF]
BMC Public HealthScouvemont M +7 more
europepmc +1 more source
Advanced Science, EarlyView.BioE is a new diiron oxygenase that catalyzes the conversion of long‐chain acyl groups into pimeloyl thioester, initiating biotin synthesis. The overexpression of EmBioE disrupts lipid metabolic homeostasis, requiring repressor BioL to maintain a balance between long‐chain fatty acids and biotin synthesis.
Meng Zhang +9 more
wiley +1 more source
Quantifying the effects of the Correa pathway from Helicobacter pylori infection to gastric cancer: causal inference found in 6.8 million Koreans. [PDF]
BMC CancerOh HJ, Kim CH, Park HW, Park B.
europepmc +1 more source
The Disordered Region of ASXL1 Acts as an Auto‐Regulator Through Condensation
Advanced Science, EarlyView.ASXL1's long IDR encodes an electrostatic “basic platform + acidic brake” that autoregulates condensation. Truncation at a clinical hotspot lifts this brake, forming condensates that retarget BRD2, remodel local chromatin accessibility, and impair neutrophil maturation.
Xiao Fang, Qiwei Li, Wenqing Zhang
wiley +1 more source
Inferring Fine-Scale Mutation and Recombination Rate Maps in Aye-Ayes (<i>Daubentonia madagascariensis</i>). [PDF]
Ecol EvolSoni V +4 more
europepmc +1 more source