Results 31 to 40 of about 683,095 (263)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Establishing Age- and Sex-Specific Reference Intervals for Thyroid Function Tests in the Older People of Eastern Anatolia: A Population-Based Indirect Approach

Medicina
Background and Objectives: Given that hormone levels vary with age, the application of age-specific reference intervals in older populations is clinically essential. In this study, we aimed to establish age- and sex-specific reference intervals (RIs) for
Zekiye Çatak, Harun Fener, Hakan Ayyıldız, Zeynep Şimal Çokgüler   +3 more
doaj   +1 more source

Optimal Swing up of Double Inverted Pendulum using Indirect Method [PDF]

International Journal of Advanced Design and Manufacturing Technology, 2018
In this paper, optimal swing up of a double inverted pendulum (DIP) with two underactuated degrees of freedom (DOFs) is solved using the indirect solution of optimal control problem.
Maral Salehi, Amin Nikoobin, Ebrahim Shahab   +2 more
doaj  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Indirect Estimation of Seagrass Frontal Area for Coastal Protection: A Mask R-CNN and Dual-Reference Approach

Journal of Marine Science and Engineering
Seagrass constitutes a vital component of coastal ecosystems, providing a wide array of ecosystem services. The accurate measurement of the seagrass frontal area is crucial for assessing its capacity to inhibit water flow and reduce wave energy; however,
Than Van Chau, Somi Jung, Minju Kim, Won-Bae Na   +3 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

THE IMPORTANCE OF CASH FLOW IN UNDERLINING COMPANIES FINANCIAL POSITION [PDF]

Analele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie, 2015
Cash-flow analysis involves the movement of cash into and out of the business in order to determine the company behavior regarding actions that create and those who consume cash in a business cycle.
ANAMARIA MORAR
doaj  

A Comparison of Result Reliability for Investigation of Milk Composition by Alternative Analytical Methods in Czech Republic

Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2014
The milk analyse result reliability is important for assurance of foodstuff chain quality. There are more direct and indirect methods for milk composition measurement (fat (F), protein (P), lactose (L) and solids non fat (SNF) content).
Oto Hanuš, Jan Říha, Eva Samková, David Ledvina, Gustav Chládek, Josef Kučera, Petr Roubal, Radoslava Jedelská, Jaroslav Kopecký   +8 more
doaj   +1 more source