Results 31 to 40 of about 3,370,294 (295)

Selection on mutators is not frequency-dependent

open access: yeseLife, 2019
The evolutionary fate of mutator mutations – genetic variants that raise the genome-wide mutation rate – in asexual populations is often described as being frequency (or number) dependent.
Yevgeniy Raynes, Daniel Weinreich
doaj   +1 more source

Haloperidol Selectively Remodels Striatal Indirect Pathway Circuits [PDF]

open access: yesNeuropsychopharmacology, 2016
Typical antipsychotic drugs are widely thought to alleviate the positive symptoms of schizophrenia by antagonizing dopamine D2 receptors expressed by striatal spiny projection neurons (SPNs). What is less clear is why antipsychotics have a therapeutic latency of weeks.
Luke E, Sebel   +3 more
openaire   +2 more sources

Variation for Nitrogen Use Efficiency Traits in Wheat Under Contrasting Nitrogen Treatments in South-Eastern Europe

open access: yesFrontiers in Plant Science, 2021
Wheat cultivars differ in their response to nitrogen (N) fertilizer, both in terms of its uptake and utilization. Characterizing this variation is an important step in improving the N use efficiency (NUE) of future cultivars while maximizing production ...
Marko Ivić   +18 more
doaj   +1 more source

Genetic and phenotypic correlations among feed efficiency, production and selected conformation traits in dairy cows

open access: yesAnimal, 2016
The difficulties and costs of measuring individual feed intake in dairy cattle are the primary factors limiting the genetic study of feed intake and utilisation, and hence the potential of their subsequent industry-wide applications.
G. Manafiazar   +6 more
doaj   +1 more source

Effect of three environments on the efficiency of indirect selection in Eragrostis curvula (lovegrass) genotypes [PDF]

open access: yes, 2003
A significant genotype environment interaction can limit gains in selecting superior genotypes since the best genotype in one locality may not be the best one in another locality. The efficiency of indirect selection is related to the heritability of the
Di Renzo, Miguel Angel   +5 more
core   +1 more source

The evaluation of elite lines obtained from red common bean (Phaseolus vulgaris L.) local populations [PDF]

open access: yesپژوهش‌های حبوبات ایران, 2020
Introduction Phaseolous vulgaris is highly important among bean species. China, Iran and Japan are the most important countries producing bean in Asia. According to reported information, cultivated area of bean was 94000 ha in Iran which 17841 ha located
Mohammad Hasan Kooshki   +1 more
doaj   +1 more source

Domestication syndrome via indirect selection in simulated cereal grains [PDF]

open access: yes, 2023
Domestication syndrome in cereal grains is commonly thought to be the product of domestication through a combination of direct artificial selection and indirect natural selection by humans. We propose an agent-based model of grain domestication.
Chebib, Jobran; id_orcid   +1 more
core   +1 more source

Density influences the heritability and genetic correlations of fish behaviour under trawling‐associated selection

open access: yesEvolutionary Applications, 2021
Fishing‐associated selection is one of the most important human‐induced evolutionary pressures for natural populations. However, it is unclear whether fishing leads to heritable phenotypic changes in the targeted populations, as the heritability and ...
Amélie Crespel   +5 more
doaj   +1 more source

Shaping ceramics through indirect selective laser sintering [PDF]

open access: yesRapid Prototyping Journal, 2016
PurposeThe purpose of this paper is to compare different powder metallurgy (PM) processes to produce ceramic parts through additive manufacturing (AM). This creates the potential to rapidly shape ceramic parts with an almost unlimited shape freedom. In this paper, alumina (Al2O3) parts are produced, as Al2O3is currently the most commonly used ceramic ...
Deckers, Jan   +5 more
openaire   +1 more source

Venetoclax‐Based Therapy as a Bridge to Hematopoietic Stem Cell Transplantation in Relapsed or Refractory Pediatric Acute Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman   +9 more
wiley   +1 more source

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