Results 51 to 60 of about 3,370,294 (295)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Genotypic and Phenotypic Association of Agronomic Features in Triticale Genotypes under Drought Stress Conditions [PDF]

پژوهشنامه اصلاح گیاهان زراعی
Extended Abstract Background: Many efforts have been made to combine the diverse capabilities of different plant species into a unique plant to increase the quantity and quality of the food product.
Hassan Basiri, Omid Alizadeh, Forud Bazrafshan, Mehdi Zare, Mohammad Yazdani   +4 more
doaj  

Indirect response in genome wide selection using selected markers

Bioscience Journal, 2019
The goal of this work was to compare the effect of the accuracy and residual variance in genome wide selection using marker selection as well as using the effect of the indirect selection, using simulated and real data. In simulated data was used one sample with 200 individuals with 1,000 molecular markers in F2 population.
Bhering, Leonardo Lopes, Xu, Shizhong
openaire   +5 more sources

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Role of allelochemicals and trichome density in the resistance of tomato to whitefly Papel de aleloquímicos e densidade de tricomas na resistência de tomateiro à mosca-branca

Ciência e Agrotecnologia, 2013
In Brazil, the tomato is cultivated in almost all geographic regions even though its yield is significantly reduced by pests and diseases. Among these pests and diseases, whitefly is a major problem that causes direct and indirect damage due to its role ...
Irã Pinheiro Neiva, Valter Carvalho de Andrade Júnior, Wilson Roberto Maluf, Celso Mattes Oliveira, Gabriel Mascarenhas Maciel   +4 more
doaj  

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Análise de trilha usando valores fenotípicos e genotípicos para componentes do rendimento na seleção de famílias de cana-de-açúcar Path analysis using phenotypic and genotypic values for yield components in the selection of sugarcane families

Ciência Rural, 2012
O objetivo deste trabalho foi investigar o uso de valores fenotípicos e genotípicos na análise de trilha envolvendo características agronômicas em cana-de-açúcar, nos estágios de cana-planta e cana-soca.
Deiciana Pagano Espósito, Luiz Alexandre Peternelli, Thiago Otávio Mendes de Paula, Márcio Henrique Pereira Barbosa   +3 more
doaj  

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source