Results 81 to 90 of about 3,370,294 (295)

Plant breeding with marker-assisted selection in Brazil [PDF]

Crop Breeding and Applied Biotechnology, 2014
Over the past three decades, molecular marker studies reached extraordinary advances, especially for sequencing and bioinformatics techniques. Marker-assisted selection became part of the breeding program routines of important seed companies, in ...
Ney Sussumu Sakiyama, Helaine Christine Cancela Ramos, Eveline Teixeira Caixeta, Messias Gonzaga Pereira   +3 more
doaj  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Other title: Title from HTML header (viewed Nov. 9, 2011): Judicial Selection Commission

, 2017
Updated irregularly; Began in 2002?; Title from main search screen (publisher's Web site, viewed Nov. 9, 2011).; At head of title: State of Connecticut.; Harvested from the web on 5/8/17Official website of the Connecticut Judicial Selection Commission ...

core   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Dependence of the yield in late-generation lines on the spike productivity in original segregating populations of spring bread wheat

Труды по прикладной ботанике, генетике и селекции
Background. An ascertained possibility of culling segregating populations on the basis on their yield or grain weight per spike as a character closely correlated with yield can increase the efficiency of breeding practice with spring bread wheat ...
S. B. Lepekhov
doaj   +1 more source

Longitudinal analyses of correlated response efficiencies of fillet traits in Nile tilapia

Animal, 2018
Recent studies with Nile tilapia have shown divergent results regarding the possibility of selecting on morphometric measurements to promote indirect genetic gains in fillet yield (FY).
E.M. Turra, A.F.A. Fernandes, E.R. de Alvarenga, E.A. Teixeira, G.F.O. Alves, L.G. Manduca, T.W. Murphy, M.A. Silva   +7 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Controlling Indirect Selection under Healthcare Reform

, 2019
Controlling Indirect Selection under Healthcare ...
Tia Sawhney (7932473)
core  

Diallel crossing in Pinus cembra : IV. Age trends in genetic parameters and genetic gain for growth and branching traits [PDF]

Annals of Forest Research, 2008
This paper reports results from a complete 10 x 10 diallel carried out in a natural population of Swiss stone pine (Pinus cembra L.) from the southern Carpathian Mountains.
Ioan Blada, Flaviu Popescu
doaj