Results 161 to 170 of about 2,125,910 (378)

DualPG‐DTA: A Large Language Model‐Powered Graph Neural Network Framework for Enhanced Drug‐Target Affinity Prediction and Discovery of Novel CDK9 Inhibitors Exhibiting in Vivo Anti‐Leukemia Activity

open access: yesAdvanced Science, EarlyView.
This study introduces DualPG‐DTA, a framework integrating two pre‐trained models to generate molecular and protein representations. It constructs dual graphs processed by specialized neural networks with dynamic attention for feature fusion, achieving superior benchmark performance.
Yihao Chen   +7 more
wiley   +1 more source

Catalyst‐Free Collagen Filament Crosslinking for Engineering Anisotropic and Mechanically Robust Tissue Scaffolds

open access: yesAdvanced Science, EarlyView.
A bioorthogonal rhodamine/PEG crosslinking strategy is introduced to engineer dense collagen hydrogels with high mechanical resilience and cytocompatibility. Integration with wet‐spinning enables the fabrication of uniaxially aligned, cell‐laden collagen filaments that activate mechanotransductive signaling and support functional muscle regeneration in
JuYeon Kim   +4 more
wiley   +1 more source

AN ANALYSIS ON STUDENTS’ ERRORS IN USING DIRECT AND INDIRECT SPEECH IN SENTENCES AT SIXTH SEMESTER STUDENTS OF STAI HUBBULWATHAN DURI

open access: yesAl-Ishlah: Jurnal Pendidikan, 2017
Based on the researchers’ observation, it was found that most of the students get difficult in using direct and indirect speech of statement. They get difficult to change tenses, pronoun and adverb of time from direct into indirect speech.
Mohd. Rafi Riyawi, Deby Alwiyah
doaj  

THE IMPLEMENTATION OF TEACHING GRAMMAR AT MAN MALANG 1 [PDF]

open access: yes, 2006
In this study, the writer interested to investigate the implementation of teaching grammar at MAN Malang 1. The purpose of this study was to investigate the objective of teaching grammar, the topic of teaching grammar, the technique of teaching grammar ...
FAJARIYAH, DEWI
core  

Convergent and Divergent Connectivity Patterns of the Arcuate Fasciculus in Macaques and Humans

open access: yesAdvanced Science, EarlyView.
This study employs viral‐based single‐neuron tracing and dMRI‐based whole‐brain tractography to investigate arcuate fasciculus (AF) trajectories in macaque monkeys, and compares with the human AF connectome using spectral embedding. Results demonstrate conserved AF topography spanning temporoparietal‐auditory‐frontal pathways across primates, with ...
Jiahao Huang   +17 more
wiley   +1 more source

The Microbiota Shapes Central Nervous System Myelination in Early Life

open access: yesAdvanced Science, EarlyView.
Gut microbiota shapes brain development by regulating myelination and glial cell maturation in early life. Using germ‐free (GF) mice and zebrafish, this study reveals sex‐ and age‐dependent effects on myelin growth, integrity, and related gene expression.
Caoimhe M. K. Lynch   +13 more
wiley   +1 more source

Evaluating Large language models on Understanding Korean indirect Speech acts [PDF]

open access: green
Youngeun Koo   +4 more
openalex   +1 more source

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