Results 1 to 10 of about 114,589 (209)

Dissecting genetic effects with imprinting

Frontiers in Ecology and Evolution, 2014
Models of genetic effects are mathematical representations of a genotype-to-phenotype (GP) map that, rather than accounting for a raw map assigning phenotypes to genotypes, rely on parameters with deliberate evolutionary meaning—additive and interaction ...
José M eÁlvarez-Castro, José M eÁlvarez-Castro   +1 more
doaj   +3 more sources

Joint analysis of SNP and gene expression data in genetic association studies of complex diseases [PDF]

, 2014
Genetic association studies have been a popular approach for assessing the association between common Single Nucleotide Polymorphisms (SNPs) and complex diseases.
Huang, Yen-Tsung, Lin, Xihong, VanderWeele, Tyler J.   +2 more
core   +1 more source

The fading of Cassiopeia A, and improved models for the absolute spectrum of primary radio calibration sources [PDF]

, 2017
Based on five years of observations with the 40-foot telescope at Green Bank Observatory (GBO), Reichart & Stephens (2000) found that the radio source Cassiopeia A had either faded more slowly between the mid-1970s and late 1990s than Baars et al. (1977)
Barlow, B. N., Berger, T. A., Dutton, D. A., Egger, R. E., Foster, A. C., Frank, N. R., Ghigo, F. D., Haislip, J. B., Heatherly, S. A., Kouprianov, V. V., Kumar, N. D., LaCluyzé, A. P., Maples, M. P., Martin, J. R., Moffett, D. A., Moore, J. P., Paggen, M. L., Reichart, D. E., Reichart, J. E., Stanley, J. L., Stýblová, J., Trotter, A. S., White, S.   +22 more
core   +3 more sources

Application of pharmacogenomics and bioinformatics to exemplify the utility of human ex vivo organoculture models in the field of precision medicine [PDF]

, 2019
Here we describe a collaboration between industry, the National Health Service (NHS) and academia that sought to demonstrate how early understanding of both pharmacology and genomics can improve strategies for the development of precision medicines ...
A Cilli, AA Agyeman, AE Tilley, AL Chokas, AV Biankin, C-H Chou, Carolyn Low, Colin N. A. Palmer, D Cook, David C. Bunton, David Mallinson, E Arif, Elaine M. Gourlay, Erika Cecchin, G Faura Tellez, Graeme Macluskie, H Yang, Hannah Child, J Milara, J-R Yu, Jane Hair, K Linhart, Karen Cowan, Linda Cheyne, M Zanoni, Marian McNeil, Max Bylesjo, ME Ezzie, Michael Finch, MR Trusheim, NJ Schork, PA André, Pamela Brankin, RC Gentleman, S Purcell, Sarah Lynagh, SI Rennard, SJ Mandrekar, SM Paul, T Yang, W Asghar, WE Johnson, Y Chen   +42 more
core   +2 more sources

A synthesis of logic and biology in the design of dependable systems [PDF]

, 2015
The technologies of model-based design and dependability analysis in the design of dependable systems, including software intensive systems, have advanced in recent years.
Papadopoulos, Yiannis
core   +1 more source

Cellular Classes in the Human Brain Revealed In Vivo by Heartbeat-Related Modulation of the Extracellular Action Potential Waveform [PDF]

, 2020
Determining cell types is critical for understanding neural circuits but remains elusive in the living human brain. Current approaches discriminate units into putative cell classes using features of the extracellular action potential (EAP); in absence of
Anastassiou, Costas A., Kamiński, Jan, Mamelak, Adam N., Mosher, Clayton P., Nandi, Anirban, Rutishauser, Ueli, Wei, Yina   +6 more
core  

Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead. [PDF]

, 2015
Lifestyle factors are responsible for a considerable portion of cancer incidence worldwide, but credible estimates from the World Health Organization and the International Agency for Research on Cancer (IARC) suggest that the fraction of cancers ...
Ab Hamid, Hasiah, Abd Hamid, Roslida, Ahmed, Nuzhat, Al-Mulla, Fahd, Al-Temaimi, Rabeah, Ali, Abdul Manaf, Amedei, Amedeo, Andrade-Vieira, Rafaela, Azqueta, Amaya, Baglole, Carolyn J., Barclay, Barry J., Bay, Sarah N., Berg, Arthur, Bisson, William H., Blanco-Aparicio, Carmen, Brooks, Samira A., Brown, Dustin G., Brunborg, Gunnar, Calaf, Gloria M., Carlin, Danielle J., Carnero, Amancio, Carpenter, David O., Casey, Stephanie C., Castellino, Robert C., Chapellier, Marion, Charles, Amelia K., Chen, Tao, Chen, Zhenbang, Cheng, Qiang (Shawn), Chiaradonna, Ferdinando, Christopher, Joseph A., Cohen-Solal, Karine A., Colacci, Annamaria, Collins, Andrew R., Corsini, Emanuela, Cruickshanks, Nichola, Curran, Colleen S., D'Abronzo, Leandro S., Darbre, Philippa, Darroudi, Firouz, de Cerain Salsamendi, Adela Lopez, Decker, William K., Dent, Paul, Di Fiore, Riccardo, Dong, Chenfang, Dormoy, Valerian, Dornetshuber-Fleiss, Rita, Eltom, Sakina, Engstrom, Wilhelm, Eriksson, Staffan, Felsher, Dean W., Fernando Martinez-Leal, Juan, Forte, Stefano, Ghosh, Paramita M., Gilbertson, Michael, Goldberg, Gary S., Gonzalez, Laetitia, Gonzalez, Michael J., Goodson, William H, Guarnieri, Tiziana, Gulliver, Linda, Harris, Shelley A., Heneberg, Petr, Hsu, Chia-Wen, Hsu, Hsue-Yin, Hu, Zhiwei, Hultman, Tove, III, Jian, Le, Karamouzis, Michalis V., Khatami, Mahin, Kirsch-Volders, Micheline, Klaunig, James E., Kleinstreuer, Nicole, Koch, Daniel C., Kondoh, Hiroshi, Koppen, Gudrun, Koturbash, Igor, Kravchenko, Julia, Krishnakumar, P. K., Krishnan, Harini, Kuemmerle, Nancy B., Laconi, Ezio, Laird, Dale W., Langie, Sabine A. S., Lasfar, Ahmed, Lee, Tae-Jin, Leung, Po Sing, Leyns, Luc, Li, Lin, Lin, Liang-Tzung, Lleonart, Matilde, Lowe, Leroy, Luanpitpong, Sudjit, Luqmani, Yunus, Lyerly, H. Kim, Maguer-Satta, Veronique, Manjili, Masoud H., Marignani, Paola A., Marongiu, Fabio, Martin, Francis L., Massfelder, Thierry, McCawley, Lisa J., Mehta, Rekha, Memeo, Lorenzo, Miousse, Isabelle R., Mondello, Chiara, Moon, Eun-Yi, Moorwood, Kim, Nahta, Rita, Nangami, Gladys, Nangia-Makker, Pratima, Narayanan, Kannan Badri, Naus, Christian C., Ochieng, Josiah, Odero-Marah, Valerie, Ogunkua, Olugbemiga, Olsen, Ann-Karin, Ostrosky-Wegman, Patricia, Otsuki, Takemi, Palorini, Roberta, Papagerakis, Silvana, Park, Hyun Ho, Pavanello, Sofia, Ponce-Cusi, Richard, Prudhomme, Kalan R., Raju, Jayadev, Rathmell, W. Kimryn, Ratovitski, Edward, Robey, R. Brooks, Rojanasakul, Yon, Rojas, Emilio, Roman, Jesse, Romano, Maria Fiammetta, Romano, Simona, Roy, Debasish, Roy, Rabindra, Ryan, Elizabeth P., Ryeom, Sandra, Sabbisetti, Venkata, Salem, Hosni K., Salzberg, Anna C., Sanderson, Thomas, Scovassi, A. Ivana, Singh, Neetu, Sinha, Ranjeet K., Sone, Hideko, Soucek, Laura, Sun, Jun, Thompson, Patricia, Vaccari, Monica, Vadgama, Pankaj, Valverde, Mahara, van Larebeke, Nik, Van Schooten, Frederik J., Vento, Renza, Vermeulen, Louis, Vondracek, Jan, Wade, Mark, Wagemaker, Gerard, Ward, Andrew, Weisz, Judith, Whitfield, Jonathan R., Williams, Graeme, Williams, Marc A., Wise, John Pierce, Sr., Wise, Sandra S., Wolf, Gregory T., Woodrick, Jordan, Xia, Menghang, Yasaei, Hemad, Yedjou, Clement, Zhang, Luoping, Zhou, Binhua P.   +173 more
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Adjustment of model parameters to estimate distribution transformers remaining lifespan [PDF]

, 2018
Currently, the electrical system in Argentina is working at its maximum capacity, decreasing the margin between the installed power and demanded consumption, and drastically reducing the service life of transformer substations due to overload (since the ...
Gotay Sardiñas, Jorge, Jimenez, Victor Adrian, Rodriguez, Sebastian Alberto, Will, Adrian L. E.   +3 more
core   +1 more source

Epigenetic Biomarkers for Environmental Exposures and Personalized Breast Cancer Prevention. [PDF]

, 2020
Environmental and lifestyle factors are believed to account for >80% of breast cancers; however, it is not well understood how and when these factors affect risk and which exposed individuals will actually develop the disease.
Park, Hannah Lui
core   +1 more source

forqs: Forward-in-time Simulation of Recombination, Quantitative Traits, and Selection [PDF]

, 2013
forqs is a forward-in-time simulation of recombination, quantitative traits, and selection. It was designed to investigate haplotype patterns resulting from scenarios where substantial evolutionary change has taken place in a small number of generations ...
Kessner, Darren, Novembre, John
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