Results 91 to 100 of about 5,637,464 (268)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Frontiers in Political ScienceWith growing availability of large-scale international surveys, social scientists are increasingly interested in comparing relations among latent variables, such as values and attitudes, across countries using Multigroup or Multilevel Structural Equation
Meijun Yao +4 more
doaj +1 more source
Individual Home Advantage with Individual Data
, 2021 Home advantage (HA) is a well-documented phenomenon in (professional) team sports. However, there is also a growing body of evidence that in individual sports home athletes have an advantage. I define HA as ‘the performance advantage of an athlete, team, or country when they compete at a home ground compared to their performance under similar ...
openaire +2 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Advances in Methods and Practices in Psychological ScienceExperience-sampling-method (ESM) studies have become a very popular tool to gain insight into the dynamics of psychological processes. Although the statistical modeling of ESM data has been widely studied, the preprocessing steps that precede such ...
Jordan Revol +5 more
doaj +1 more source
The use of data analytics for management decision–making in retail
Ученые записки Российской академии предпринимательстваThe use of data analytics in retail is a key factor for making effective management decisions aimed at increasing competitiveness and optimizing business processes.
V. P. Makarov
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Gaze cluster analysis reveals heterogeneity in attention allocation and predicts learning outcomes
Scientific ReportsInstructional videos need to maintain learners’ attention to foster learning, therefore, a fine-grained measurement of attention is required. Existing gaze measures like inter-subject correlation (ISC) assume a singular focal point deemed meaningful for ...
Nathalie John +3 more
doaj +1 more source
The Prevalence of Armed Kidnapping in Hungary
Belügyi SzemleAim: The aim of the article is to review and understand how the crime of armed kidnapping was present in the latest 30 years in Hungary, including various types of statistics and their comparison.
Mariann Minkó-Miskovics
doaj +1 more source