Results 171 to 180 of about 2,863,971 (312)

Individual characteristics and work-related outcomes

, 2013
Contains fulltext : 119788.pdf (Publisher’s version ) (Open Access)
Van der Heijden, BIJM, Van Dam, K., Xanthopoulou, D., De Lange, A.   +3 more
openaire   +3 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Individual characteristics associated with youth symptom reports and persisting symptoms after concussion. [PDF]

J Neuropsychol
Hicks SD, Harding BA, Olympia R, Loeffert J, Onks C, Mannix RC, Levine DA, Yeates KO.   +7 more
europepmc   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

A systematic review on the effect of individual characteristics and management practices on equine cognition. [PDF]

Anim Cogn
Ricci-Bonot C, Brosche K, Baragli P, Nicol C.   +3 more
europepmc   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

What are the Individual Characteristics or Skills Associated with Baseball Batting Performance? A Scoping Review. [PDF]

Sports Med Open
Tremblay M, Couëpel B, Abboud J, Descarreaux M.   +3 more
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Individual Characteristics and National Income Modify the Association between Cognitive Social Capital and Food Insecurity: Evidence from the Gallup World Poll, 2014-2021. [PDF]

Curr Dev Nutr
Isanovic S, O'Connor K, Richards AL, Frongillo EA.   +3 more
europepmc   +1 more source

Extracting proficiency differences and individual characteristics in golfers' swing using single-video markerless motion analysis. [PDF]

Front Sports Act Living, 2023
Yamamoto K, Hasegawa Y, Suzuki T, Suzuki H, Tanabe H, Fujii K.   +5 more
europepmc   +1 more source