Results 251 to 260 of about 2,863,971 (312)

From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care

open access: yesMolecular Oncology, EarlyView.
Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard   +8 more
wiley   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant   +11 more
wiley   +1 more source

Individual characteristics

open access: yes, 2013
Individual characteristics.
Gautam Hebbar (448715)   +6 more
openaire   +2 more sources
Some of the next articles are maybe not open access.

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Individual behavioural characteristics in pigs

Applied Animal Behaviour Science, 1993
Abstract In two identical experiments a total of 218 piglets from 20 sows were used to test if consistent individual behavioural differences exist among pigs. At an age of 1–2 weeks piglets were divided between aggressive and non-aggressive individuals on the basis of their behaviour in two successive social confrontation tests (SC1 and SC2 ...
Hessing, M.J.C.   +5 more
openaire   +2 more sources

Individual Characteristics of Human Spermatozoa

Archives of Andrology, 1980
We have investigated the variability of some characteristics of a sperm sample in 18 young volunteers in good health who were examined twice per month over a period of two years, and in about one hundred men undergoing treatment for sterility and for whom more than 4 spermiograms had been established during the past three years.
C, Souchier   +3 more
openaire   +2 more sources

The Characteristic Thesis of Anti‐Individualism

Analysis, 1995
(To say that p metaphysically depends upon q is to say that it is metaphysically necessary that if p, then q.) McKinsey presents the following argument against anti-individualism. We start with a plausible Kripkean essentialist premiss which 'most individualists would gladly accept' ([7], p.
openaire   +1 more source

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